Racial differences in dermatologic conditions associated with HIV: A cross-sectional study of 4679 patients in an urban tertiary care center

被引:16
作者
Bender, Alexandra M. [1 ]
Tang, Olive [1 ]
Khanna, Raveena [1 ]
Staender, Sonja [2 ]
Kang, Sewon [1 ]
Kwatra, Shawn G. [1 ,3 ]
机构
[1] Johns Hopkins Univ, Sch Med, Dept Dermatol, Baltimore, MD USA
[2] Univ Munster, Ctr Chron Pruritus, Dept Dermatol, Munster, Germany
[3] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
关键词
antiretroviral therapy; human immunodeficiency virus; Kaposi sarcoma; oral hairy leukoplakia; prurigo nodularis; pruritus; THERAPY;
D O I
10.1016/j.jaad.2019.08.072
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Because of reduced mortality, patients with HIV are living longer and presenting with chronic diseases. Little is known about racial differences in dermatologic conditions associated with HIV infection. Objective: This study examines associated dermatologic conditions in a large population of patients with HIV at a tertiary care center with a diverse patient population. Methods: Cross-sectional study of patients with HIV seen between July 14, 2013, and July 14, 2018, in a tertiary health care system. The burden of HIV-related dermatologic conditions was collected by using medical records. Patients with HIV were compared with control individuals of the same race, and significance was assessed using the chi-square test. A Bonferroni correction was performed to control for multiple hypothesis testing. Results: The study population (N = 4679) was 64.7% male and 69% African American, with 88.7% of patients receiving antiretroviral therapy. African American patients with HIV had a greater risk of oral hairy leukoplakia (odds ratio [OR], 64.49), herpes zoster (OR, 9.27), prurigo nodularis (OR, 8.80), and squamous cell carcinoma (OR, 5.72). Limitations: Our data describe patients seen by 1 health care system. Conclusions: African American patients with HIV may be at increased risk for pruritic disorders compared with race-matched control individuals and white patients with HIV.
引用
收藏
页码:1117 / 1123
页数:7
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