The Short-Term Remission of Diabetic Nephropathy After Roux-en-Y Gastric Bypass in Chinese Patients of T2DM with Obesity

被引:17
作者
Zhang, Hongwei [1 ]
Di, Jianzhong [1 ]
Yu, Haoyong [2 ]
Han, Xiaodong [1 ]
Li, Kun [1 ]
Zhang, Pin [1 ]
机构
[1] Shanghai Jiao Tong Univ, Dept Gen Surg, Peoples Hosp 6, Shanghai 200233, Peoples R China
[2] Shanghai Jiao Tong Univ, Dept Endocrinol & Metab, Peoples Hosp 6, Shanghai 200233, Peoples R China
关键词
Gastric bypass; Type 2 diabetes mellitus; Diabetic nephropathy; Microalbuminuria; Albumin/creatinine ratio; BARIATRIC SURGERY; KIDNEY-DISEASE; MEDICAL THERAPY; PROGRESSION; COMPLICATIONS;
D O I
10.1007/s11695-015-1666-y
中图分类号
R61 [外科手术学];
学科分类号
摘要
The study aimed to examine the effect of gastric bypass on diabetic nephropathy (DN) in Chinese patients. A retrospective study of 101 samples with DN stages I to IV underwent Roux-en-Y gastric bypass. Anthropometric and biochemical parameters were assessed during a 1-year follow-up. Binary logistic regression analysis was used for predictors and ROC for cutoff points. There was significant reduction of medication for diabetes and hypertension. Overall remission of T2DM was 80.2 %. Preoperative albumin/creatinine ratio (ACR) and serum creatinine (SCr) levels could be predictors for DN remission, and the cutoff points were 126 mg/g cr and 57 mu mol/L, respectively. Gastric bypass showed improvement of T2DM and DN. Gastric bypass may be more beneficial for those with lower preoperative ACR and SCr.
引用
收藏
页码:1263 / 1270
页数:8
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