Imaging of ovarian cancers using enzyme activatable probes with second near-infrared window emission

被引：57

作者：

Chen, Ji-An ^{[1
]}

Pan, Hongming ^{[2
]}

Wang, Zhijun ^{[2
]}

Gao, Jie ^{[1
]}

Tan, Jiahui ^{[1
]}

Ouyang, Zhirong ^{[1
]}

Guo, Wei ^{[2
]}

Gu, Xianfeng ^{[1
]}

机构：

[1] Fudan Univ, Sch Pharm, Dept Med Chem, Shanghai 201301, Peoples R China

[2] Fudan Univ, Sch Pharm, Dept Pharmacol, Shanghai 201301, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 18期

关键词：

BETA-GALACTOSIDASE ACTIVITY; SELECTIVE DETECTION; FLUORESCENT-PROBE; STRUCTURAL BASIS; TRACKING; DESIGN; TUMOR; FLUOROPHORES; NANOPROBE; BRIGHT;

D O I：

10.1039/c9cc09158k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We herein develop two beta-galactosidase (beta-Gal) activatable NIR fluorescent probes for visualizing ovarian cancers. Particularly, probe BOD-M-beta Gal produced NIR-II emission light at 900-1300 nm upon beta-Gal activation. By using our activatable and target specific NIR-II probe for deep-tissue imaging of beta-Gal overexpressed ovarian cancer cells, rapid and accurate imaging of ovarian tumors in nude mice was achieved.

引用

页码：2731 / 2734

页数：4

共 50 条

[31] The Midas Touch by Internal Stimuli: Activatable Luminogens with Near-Infrared Aggregation-Induced Emission for Potent Bioimaging and Theranostics
Gao, Yiting
Yan, Dingyuan
Yang, Xinyue
Huang, Weigeng
Sun, Yan
Zhu, Dongxia
Liu, Qian
Shan, Guogang
Wang, Dong
Tang, Ben Zhong
ADVANCED FUNCTIONAL MATERIALS, 2024, 34 (52)
[32] Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes
Shieh, Peyton
Siegrist, M. Sloan
Cullen, Andrew J.
Bertozzi, Carolyn R.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (15) : 5456 - 5461
[33] Recent Progress in Fluorescence Imaging of the Near-Infrared II Window
Miao, Yawei
Gu, Chuantao
Zhu, Yaowei
Yu, Bing
Shen, Youqing
Cong, Hailin
CHEMBIOCHEM, 2018, 19 (24) : 2522 - 2541
[34] Hydrogen Sulfide-Activatable Second Near-Infrared Fluorescent Nanoassemblies for Targeted Photothermal Cancer Therapy
Shi, Ben
Yan, Qinglong
Tang, Jie
Cin, Kai
Zhang, Jichao
Zhu, Ying
Xu, Ge
Wang, Rongchen
Chen, Jian
Gao, Wei
Zhu, Tianli
Shi, Jiye
Fan, Chunhai
Zhao, Chunchang
Tian, He
NANO LETTERS, 2018, 18 (10) : 6411 - 6416
[35] Development of Second Near-Infrared Photoacoustic Imaging Agents
Zhang, Jianjian
Ning, Lulu
Zeng, Ziling
Pu, Kanyi
TRENDS IN CHEMISTRY, 2021, 3 (04): : 305 - 317
[36] A Highly Bright Near-Infrared Afterglow Luminophore for Activatable Ultrasensitive In Vivo Imaging
Yang, Li
Zhao, Min
Chen, Wan
Zhu, Jieli
Xu, Weina
Li, Qing
Pu, Kanyi
Miao, Qingqing
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024, 63 (04)
[37] An Activatable Polymeric Reporter for Near-Infrared Fluorescent and Photoacoustic Imaging of Invasive Cancer
Li, Qing
Li, Shenhua
He, Shasha
Chen, Wan
Cheng, Penghui
Zhang, Yan
Miao, Qingqing
Pu, Kanyi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 59 (18) : 7018 - 7023
[38] An IR820 Dye-Protein Complex for Second Near-Infrared Window and Photoacoustic Imaging
Du, Bulin
Qu, Chunrong
Qian, Kun
Ren, Ying
Li, Yesen
Cui, Xiaohong
He, Shuqing
Wu, Yifan
Ko, Timothy
Liu, Ruiqi
Li, Xuena
Li, Yaming
Cheng, Zhen
ADVANCED OPTICAL MATERIALS, 2020, 8 (04):
[39] A molecular design strategy toward enzyme-activated probes with near-infrared I and II fluorescence for targeted cancer imaging
Wang, Rongchen
Chen, Jian
Gao, Jie
Chen, Ji-An
Xu, Ge
Zhu, Tianli
Gu, Xianfeng
Guo, Zhiqian
Zhu, Wei-Hong
Zhao, Chunchang
CHEMICAL SCIENCE, 2019, 10 (30) : 7222 - 7227
[40] Water-soluble Ag2Te Quantum Dots with Emission in the Second Near-infrared Window
Zhou Jieqiong
Huang Yan
Zhang Zhiling
Pang Daiwen
Tian Zhiquan
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2021, 42 (06): : 2072 - 2079

← 1 2 3 4 5 →