Clinical Symptoms and Outcomes of Severe Pneumonia Caused by Chlamydia psittaci in Southwest China

被引：49

作者：

Yang, Fuxun ^{[1
]}

Li, Jiajia ^{[1
]}

Qi, Bo ^{[2
]}

Zou, Longfei ^{[3
]}

Shi, Zongming ^{[4
]}

Lei, Yu ^{[1
]}

Li, Jun ^{[5
]}

Luo, Xiaoxiu ^{[1
]}

Zeng, Fan ^{[1
]}

Lu, Sen ^{[1
]}

Huang, Xiaobo ^{[1
]}

Liu, Rongan ^{[1
]}

Lan, Yunping ^{[1
]}

机构：

[1] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Dept ICU, Chengdu, Peoples R China

[2] 903 Hosp, Dept Intens Care Unit, Mianyang, Sichuan, Peoples R China

[3] Southwest Med Univ, Dept ICU, Affiliated Hosp, Luzhou, Peoples R China

[4] Southwest Med Univ, Dept ICU, Neijiang Peoples Hosp, Neijiang, Sichuan, Peoples R China

[5] North Sichuan Med Coll, Dept ICU, Shifang City Peoples Hosp, Shifang, Peoples R China

来源：

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2022年 / 11卷

关键词：

Chlamydia psittaci; pneumonia; clinical symptoms; mNGS; ICU;

D O I：

10.3389/fcimb.2021.727594

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Here, we aimed to retrospectively analyze the clinical characteristics of 27 patients with severe pneumonia caused by Chlamydia psittaci between January 2019 and April 2021 in southwest China. To this end, we collected data on the exposure history, clinical symptoms, laboratory examination, imaging characteristics, evolution, etiology, treatment, and outcomes to suggest a better diagnosis and prevention system. Our results showed that a metagenomic next-generation sequencing test could provide early diagnosis. All patients were sensitive to quinolones and tetracyclines, and the recovery rate was relatively high. Overall, all patients were in critical condition with moderate to severe acute respiratory distress syndrome and shock. In conclusion, early diagnosis of pneumonia caused by C. psittaci depends on effective molecular testing, and most patients recover after treatment.

引用

页数：8

共 29 条

[21] Severe Chlamydia psittaci pneumonia: clinical characteristics and risk factors [J].

Su, Shanshan ;

Su, Xiaoqing ;

Zhou, Lingping ;

Lin, Pengcheng ;

Chen, Junjie ;

Chen, Chengshui ;

Zhou, Ying ;

Li, Yuping .

ANNALS OF PALLIATIVE MEDICINE, 2021, 10 (07) :8051-+

[22] Clinical Analysis of Metagenomic Next-Generation Sequencing Confirmed Chlamydia psittaci Pneumonia: A Case Series and Literature Review [J].

Teng, Xin-Qi ;

Gong, Wen-Cheng ;

Qi, Ting-Ting ;

Li, Guo-Hua ;

Qu, Qiang ;

Lu, Qiong ;

Qu, Jian .

INFECTION AND DRUG RESISTANCE, 2021, 14 :1481-1492

[23] The tetracycline resistome [J].

Thaker, Maulik ;

Spanogiannopoulos, Peter ;

Wright, Gerard D. .

CELLULAR AND MOLECULAR LIFE SCIENCES, 2010, 67 (03) :419-431

[24]

Vassallo M, 1997, INT J CLIN PRACT, V51, P261

[25] Presence of Chlamydophila psittaci DNA in the central nervous system of a patient with status epilepticus [J].

Walder, G ;

Schönherr, H ;

Hotzel, H ;

Speth, C ;

Cehme, A ;

Dierich, MP ;

Würzner, R .

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2003, 35 (01) :71-73

[26] Multiple human-to-human transmission from a severe case of psittacosis, Sweden, January-February 2013 [J].

Wallensten, A. ;

Fredlund, H. ;

Runehagen, A. .

EUROSURVEILLANCE, 2014, 19 (42) :34-39

[27]

Wreghitt T, 1993, Commun Dis Rep CDR Rev, V3, pR119

[28] Detection of Chlamydia psittaci in both blood and bronchoalveolar lavage fluid using metagenomic next-generation sequencing A case report [J].

Yuan, Yingpu ;

Zhang, Xiaobo ;

Gui, Chunmei .

MEDICINE, 2021, 100 (27)

[29] PSITTACOSIS - A REVIEW OF 135 CASES [J].

YUNG, AP ;

GRAYSON, ML .

MEDICAL JOURNAL OF AUSTRALIA, 1988, 148 (05) :228-233

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