Clinical Symptoms and Outcomes of Severe Pneumonia Caused by Chlamydia psittaci in Southwest China

被引:49
作者
Yang, Fuxun [1 ]
Li, Jiajia [1 ]
Qi, Bo [2 ]
Zou, Longfei [3 ]
Shi, Zongming [4 ]
Lei, Yu [1 ]
Li, Jun [5 ]
Luo, Xiaoxiu [1 ]
Zeng, Fan [1 ]
Lu, Sen [1 ]
Huang, Xiaobo [1 ]
Liu, Rongan [1 ]
Lan, Yunping [1 ]
机构
[1] Univ Elect Sci & Technol China, Sichuan Prov Peoples Hosp, Dept ICU, Chengdu, Peoples R China
[2] 903 Hosp, Dept Intens Care Unit, Mianyang, Sichuan, Peoples R China
[3] Southwest Med Univ, Dept ICU, Affiliated Hosp, Luzhou, Peoples R China
[4] Southwest Med Univ, Dept ICU, Neijiang Peoples Hosp, Neijiang, Sichuan, Peoples R China
[5] North Sichuan Med Coll, Dept ICU, Shifang City Peoples Hosp, Shifang, Peoples R China
来源
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY | 2022年 / 11卷
关键词
Chlamydia psittaci; pneumonia; clinical symptoms; mNGS; ICU;
D O I
10.3389/fcimb.2021.727594
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Here, we aimed to retrospectively analyze the clinical characteristics of 27 patients with severe pneumonia caused by Chlamydia psittaci between January 2019 and April 2021 in southwest China. To this end, we collected data on the exposure history, clinical symptoms, laboratory examination, imaging characteristics, evolution, etiology, treatment, and outcomes to suggest a better diagnosis and prevention system. Our results showed that a metagenomic next-generation sequencing test could provide early diagnosis. All patients were sensitive to quinolones and tetracyclines, and the recovery rate was relatively high. Overall, all patients were in critical condition with moderate to severe acute respiratory distress syndrome and shock. In conclusion, early diagnosis of pneumonia caused by C. psittaci depends on effective molecular testing, and most patients recover after treatment.
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页数:8
相关论文
共 29 条
[1]   BRAIN-STEM ENCEPHALITIS IN ORNITHOSIS [J].
ALKAWI, MZ ;
MADKOUR, MM .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1986, 49 (05) :603-604
[2]  
[Anonymous], 2000, MMWR Recomm Rep, V49, P3
[3]  
Branley J M, 2014, New Microbes New Infect, V2, P7, DOI 10.1002/2052-2975.29
[4]   Metagenomic next-generation sequencing in the diagnosis of severe pneumonias caused by Chlamydia psittaci [J].
Chen, Xiancheng ;
Cao, Ke ;
Wei, Yu ;
Qian, Yajun ;
Liang, Jing ;
Dong, Danjiang ;
Tang, Jian ;
Zhu, Zhanghua ;
Gu, Qin ;
Yu, Wenkui .
INFECTION, 2020, 48 (04) :535-542
[5]   Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance [J].
Gasparrini, Andrew J. ;
Markley, Jana L. ;
Kumar, Hirdesh ;
Wang, Bin ;
Fang, Luting ;
Irum, Sidra ;
Symister, Chanez T. ;
Wallace, Meghan ;
Burnham, Carey-Ann D. ;
Andleeb, Saadia ;
Tolia, Niraj H. ;
Wencewicz, Timothy A. ;
Dantas, Gautam .
COMMUNICATIONS BIOLOGY, 2020, 3 (01)
[6]   Multiple organ infection and the pathogenesis of SARS [J].
Gu, J ;
Gong, EC ;
Zhang, B ;
Zheng, J ;
Gao, ZF ;
Zhong, YF ;
Zou, WZ ;
Zhan, J ;
Wang, SL ;
Xie, ZG ;
Zhuang, H ;
Wu, BQ ;
Zhong, HH ;
Shao, HQ ;
Fang, WG ;
Gao, DS ;
Pei, F ;
Li, XW ;
He, ZP ;
Xu, DZ ;
Shi, XY ;
Anderson, VM ;
Leong, ASY .
JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 202 (03) :415-424
[7]   CHLAMYDIOSIS IN WORKERS AT A DUCK FARM AND PROCESSING PLANT [J].
HINTON, DG ;
SHIPLEY, A ;
GALVIN, JW ;
HARKIN, JT ;
BRUNTON, RA .
AUSTRALIAN VETERINARY JOURNAL, 1993, 70 (05) :174-176
[8]  
Hogerwerf L, 2017, EPIDEMIOL INFECT, V145, P3096, DOI [10.1017/S0950268817002060, 10.1017/s0950268817002060]
[9]   The Feasibility Study of Non-Invasive Fetal Trisomy 18 and 21 Detection with Semiconductor Sequencing Platform [J].
Jeon, Young Joo ;
Zhou, Yulin ;
Li, Yihan ;
Guo, Qiwei ;
Chen, Jinchun ;
Quan, Shengmao ;
Zhang, Ahong ;
Zheng, Hailing ;
Zhu, Xingqiang ;
Lin, Jin ;
Xu, Huan ;
Wu, Ayang ;
Park, Sin-Gi ;
Kim, Byung Chul ;
Joo, Hee Jae ;
Chen, Hongliang ;
Bhak, Jong .
PLOS ONE, 2014, 9 (10)
[10]   Chlamydia psittaci: update on an underestimated zoonotic agent [J].
Knittler, Michael R. ;
Sachse, Konrad .
PATHOGENS AND DISEASE, 2015, 73 (01)