Drug repositioning is an alternative for the treatment of coronavirus COVID-19

被引：81

作者：

Serafin, Marissa B. ^{[1
]}

Bottega, Angelita ^{[1
]}

Foletto, Vitoria S. ^{[1
]}

da Rosa, Tacieli F. ^{[1
]}

Horner, Andreas ^{[3
]}

Horner, Rosmari ^{[1
,2
]}

机构：

[1] Univ Fed Santa Maria, Programa Posgrad Ciencias Farmaceut, Santa Maria, RS, Brazil

[2] Univ Fed Santa Maria, Dept Anal Clin & Toxicol, Ave Roraima 1000 Cidade Univ, BR-97105900 Santa Maria, RS, Brazil

[3] Univ Fed Santa Maria, Posgrad Mestrado Profiss Ciencias Saude, Santa Maria, RS, Brazil

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 2020年 / 55卷 / 06期

关键词：

Repositioning; COVID-19; SARS-CoV-2; RESPIRATORY SYNDROME CORONAVIRUS; REPLICATION; CHLOROQUINE;

D O I：

10.1016/j.ijantimicag.2020.105969

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Given the extreme importance of the current pandemic caused by COVID-19, and as scientists agree there is no identified pharmacological treatment, where possible, therapeutic alternatives are raised through drug repositioning. This paper presents a selection of studies involving drugs from different pharmaceu- tical classes with activity against SARS-CoV-2 and SARS-CoV, with the potential for use in the treatment of COVID-19 disease. (C) 2020 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

引用

页数：4

共 21 条

[1] Adams S, 2019, ANN ONCOL, V30, P405, DOI [10.1093/annonc/mdy517, 10.1093/annonc/mdy518]
[2] [Anonymous], CLIN INFECT DIS
[3] Teicoplanin: an alternative drug for the treatment of COVID-19?
Baron, Sophie Alexandra
Devaux, Christian
Colson, Philippe
Raoult, Didier
Rolain, Jean-Marc
[J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2020, 55 (04)
[4] Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
de Wilde, Adriaan H.
Jochmans, Dirk
Posthuma, Clara C.
Zevenhoven-Dobbe, Jessika C.
van Nieuwkoop, Stefan
Bestebroer, Theo M.
van den Hoogen, Bernadette G.
Neyts, Johan
Snijder, Eric J.
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (08) : 4875 - 4884
[5] Cyclosporin A inhibits the replication of diverse coronaviruses
de Wilde, Adriaan H.
Zevenhoven-Dobbe, Jessika C.
van der Meer, Yvonne
Thiel, Volker
Narayanan, Krishna
Makino, Shinji
Snijder, Eric J.
van Hemert, Martijn J.
[J]. JOURNAL OF GENERAL VIROLOGY, 2011, 92 : 2542 - 2548
[6] Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
Dyall, Julie
Coleman, Christopher M.
Hart, Brit J.
Venkataraman, Thiagarajan
Holbrook, Michael R.
Kindrachuk, Jason
Johnson, Reed F.
Olinger, Gene G., Jr.
Jahrling, Peter B.
Laidlaw, Monique
Johansen, Lisa M.
Lear-Rooney, Calli M.
Glass, Pamela J.
Hensley, Lisa E.
Frieman, Matthew B.
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (08) : 4885 - 4893
[7] Repositioning of fluoxetine and paroxetine: study of potential antibacterial activity and its combination with ciprofloxacin
Foletto, Vitoria S.
Serafin, Marissa B.
Bottega, Angelita
da Rosa, Tacieli F.
Machado, Catrine de S.
Coelho, Silvana S.
Horner, Rosmari
[J]. MEDICINAL CHEMISTRY RESEARCH, 2020, 29 (03) : 556 - 563
[8] Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies
Gao, Jianjun
Tian, Zhenxue
Yang, Xu
[J]. BIOSCIENCE TRENDS, 2020, 14 (01) : 72 - 73
[9] Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
Gautret, Philippe
Lagier, Jean-Christophe
Parola, Philippe
Van Thuan Hoang
Meddeb, Line
Mailhe, Morgane
Doudier, Barbara
Courjon, Johan
Giordanengo, Valerie
Vieira, Vera Esteves
Dupont, Herve Tissot
Honore, Stephane
Colson, Philippe
Chabriere, Eric
La Scola, Bernard
Rolain, Jean-Marc
Brouqui, Philippe
Raoult, Didier
[J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2020, 56 (01)
[10] Gordon David E, 2020, bioRxiv, DOI 10.1101/2020.03.22.002386

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