Update on External Beam Radiation Therapy in Thyroid Cancer

被引：32

作者：

Brierley, James D. ^{[1
]}

机构：

[1] Univ Toronto, Princess Margaret Hosp, Dept Radiat Oncol, Toronto, ON M5G 2M9, Canada

来源：

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 2011年 / 96卷 / 08期

关键词：

HYPERFRACTIONATED ACCELERATED RADIOTHERAPY; CLINICAL-OUTCOMES; CARCINOMA; SURVIVAL; VOLUME;

D O I：

10.1210/jc.2011-1109

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Surgery is the mainstay of treatment for thyroid cancer. The role for external beam radiotherapy (EBRT) as an adjuvant to surgery or as the primary therapy is established in anaplastic thyroid cancer but is controversial in differentiated thyroid cancer and uncertain in medullary thyroid cancer. This update reviews the recent reported success of combining EBRT with taxanes in anaplastic thyroid cancer. Also discussed are the recent reports from large single institutions that support the recommendations of the American and British Thyroid Associations on the use of EBRT in high-risk differentiated thyroid cancer. Further evidence on the role of EBRT in MTC is discussed. The important advances in the delivery of EBRT using intensity-modulated radiation and image-guided radiation that result in more accurate and potentially more effective radiation therapy with less toxicity are also discussed. (J Clin Endocrinol Metab 96: 2289-2295, 2011)

引用

页码：2289 / 2295

页数：7

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