Identification of selective inhibitors of NAD plus dependent histone deacetylases.

被引:0
作者
Posakony, J
Hirao, M
Nelson, M
Stevens, S
Bedalov, A
Simon, J
Hruby, H
Jung, M
机构
[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA
[2] Univ Munster, Dept Pharmaceut & Med Chem, D-4400 Munster, Germany
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:6170S / 6170S
页数:1
相关论文
共 50 条
  • [41] The application of histone deacetylases inhibitors in glioblastoma
    Rui Chen
    Mengxian Zhang
    Yangmei Zhou
    Wenjing Guo
    Ming Yi
    Ziyan Zhang
    Yanpeng Ding
    Yali Wang
    Journal of Experimental & Clinical Cancer Research, 39
  • [42] Histone deacetylases and transcriptional therapy with their inhibitors
    Pandolfi, PP
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2001, 48 (Suppl 1) : S17 - S19
  • [43] Subtype selective substrates for histone deacetylases
    Heltweg, B
    Dequiedt, F
    Marshall, BL
    Branch, C
    Yoshida, M
    Nishino, N
    Verdin, E
    Jung, M
    JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (21) : 5235 - 5243
  • [44] Quercetin induces apoptosis in leukemia models, in part by suppressing class I histone deacetylases.
    Alvarez De Prax, M. C.
    Maso, V.
    Torello, C. O.
    Saad, S. T.
    MOLECULAR BIOLOGY OF THE CELL, 2016, 27
  • [45] Crystal structure of human HDAC8 provides insights into the class I histone deacetylases.
    Somoza, JR
    Skene, RJ
    Katz, BA
    Mol, C
    Ho, J
    Jennings, AJ
    Luong, C
    Arvai, A
    Buggy, JJ
    Chi, E
    Tang, J
    Sang, BC
    Verner, E
    Wynands, R
    Leahy, EM
    Dougan, DR
    Snell, G
    Navre, M
    Knuth, MW
    Swanson, RV
    McRee, DE
    Tari, LW
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U163 - U163
  • [46] Epigenetic reprogramming during SS-dependent differentiation of mouse embryonic stem cells: Role of nitric oxide and histone deacetylases.
    Illi, Barbara
    Spallotta, Francesco
    Mattussi, Stefania
    Capogrossi, Maurizio C.
    Gaetano, Carlo
    CIRCULATION, 2006, 114 (18) : 32 - 32
  • [47] Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia
    Min, Chengyin
    Moore, Nathan
    Shearstone, Jeffrey R.
    Quayle, Steven N.
    Huang, Pengyu
    van Duzer, John H.
    Jarpe, Matthew B.
    Jones, Simon S.
    Yang, Min
    PLOS ONE, 2017, 12 (01):
  • [48] Synthesis and biological activity of splitomicin analogs targeted at human NAD+-dependent histone deacetylases (sirtuins)
    Freitag, Marcus
    Schemies, Joerg
    Larsen, Tim
    El Gaghlab, Khattab
    Schulz, Felix
    Rumpf, Tobias
    Jung, Manfred
    Link, Andreas
    BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (12) : 3669 - 3677
  • [49] Exploration of the binding pocket of histone deacetylases: the design of potent and isoform-selective inhibitors
    Uba, Abdullahi Ibrahim
    Yelekci, Kemal
    TURKISH JOURNAL OF BIOLOGY, 2017, 41 (06) : 901 - 918
  • [50] Role of histone deacetylases and their inhibitors in neurological diseases
    Zhang, Li-Ying
    Zhang, Sen-Yu
    Wen, Ri
    Zhang, Tie-Ning
    Yang, Ni
    PHARMACOLOGICAL RESEARCH, 2024, 208