The Transmission Dynamics of Hepatitis B Virus via the Fractional-Order Epidemiological Model

被引:19
作者
Khan, Tahir [1 ,2 ,3 ]
Qian, Zi-Shan [4 ]
Ullah, Roman [5 ]
Al Alwan, Basem [6 ]
Zaman, Gul [2 ]
Al-Mdallal, Qasem M. [7 ]
El Khatib, Youssef [7 ]
Kheder, Khaled [8 ]
机构
[1] Muscat Coll, Dept Comp, Muscat, Oman
[2] Univ Malakand, Dept Math, Chakdara, Pakhtunkhwa, Pakistan
[3] Woman Univ Swabi, Dept Math & Stat, Khyber Pakhtunkhwa, Pakistan
[4] Univ Calif Irvine, Sch Phys Sci, Irvine, CA 92617 USA
[5] Univ Technol & Appl Sci, CAS Sohar, Gen Requirements Dept, Muscat, Oman
[6] King Khalid Univ, Coll Engn, Chem Engn Dept, Abha 61411, Saudi Arabia
[7] UAE Univ, Dept Math Sci, POB 15551, Al Ain, U Arab Emirates
[8] King Khalid Univ, Coll Engn, Civil Engn Dept, Abha 61411, Saudi Arabia
关键词
MATHEMATICAL-MODEL; MANAGEMENT; INFECTION;
D O I
10.1155/2021/8752161
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
We investigate and analyze the dynamics of hepatitis B with various infection phases and multiple routes of transmission. We formulate the model and then fractionalize it using the concept of fractional calculus. For the purpose of fractionalizing, we use the Caputo-Fabrizio operator. Once we develop the model under consideration, existence and uniqueness analysis will be discussed. We use fixed point theory for the existence and uniqueness analysis. We also prove that the model under consideration possesses a bounded and positive solution. We then find the basic reproductive number to perform the steady-state analysis and to show that the fractional-order epidemiological model is locally and globally asymptotically stable under certain conditions. For the local and global analysis, we use linearization, mean value theorem, and fractional Barbalat's lemma, respectively. Finally, we perform some numerical findings to support the analytical work with the help of graphical representations.
引用
收藏
页数:18
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