An Updated Review on Biologically Promising Natural Oxepines

被引：4
作者：
Mandal, Bhagirath [1 ]
Karmakar, Indrajit [1 ]
Brahmachari, Goutam [1 ]
机构：
[1] Visva Bharati, Dept Chem, Lab Nat Prod & Organ Synth, Santini Ketan 731235, W Bengal, India
来源：
CHEMISTRY & BIODIVERSITY | 2022年 / 19卷 / 10期
关键词：
benzo-oxepines; dibenzo-oxepines; secondary metabolites; natural occurrence; biosynthesis; biological profiles; FARNESYL-PROTEIN TRANSFERASE; MARINE-DERIVED FUNGUS; ENDOPHYTIC FUNGUS; ANTIINFLAMMATORY CONSTITUENTS; ALKALOIDS; ANTIMYCOBACTERIAL; POLYKETIDES; DERIVATIVES; CULARINE; FUSIDIENOL;
D O I：
10.1002/cbdv.202200484
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Benzo-oxepines and dibenzo-oxepines, a unique class of naturally occurring secondary metabolites, are distributed mainly in plants and fungi and have received much attention from phytochemists and biologists based on their fascinating structural features and health-promoting functions. This review summarizes 100 oxepine derivatives comprising three categories: benzo-oxepine, dibenzo-oxepine, and pyrano-oxepine. Studies on various structural features and pharmacological activities of oxepine derivatives promote further in-depth research on these potent natural products. This review portrays the natural occurrence, bioactivity and biosynthesis of oxepines reported from 1984 to 2021.
引用
收藏
页数：14
相关论文
共 53 条
  • [1] PACHARIN - A NEW DIBENZO(2,3-6,7)OXEPIN DERIVATIVE FROM BAUHINIA-RACEMOSA LAMK
    ANJANEYULU, ASR
    REDDY, AVR
    REDDY, DSK
    WARD, RS
    ADHIKESAVALU, D
    CAMERON, TS
    [J]. TETRAHEDRON, 1984, 40 (21) : 4245 - 4252
  • [2] SECOCULARINES - A NEW GROUP OF ISOQUINOLINE RELATED ALKALOIDS PRESENT IN THE FUMARIACEAE
    BOENTE, JM
    CASTEDO, L
    DOMINGUEZ, D
    FARINA, A
    DELERA, AR
    VILLAVERDE, MC
    [J]. TETRAHEDRON LETTERS, 1984, 25 (08) : 889 - 892
  • [3] CELTINE, CELTISINE AND BREOGANINE, NEW PHENOLIC CULARINE ALKALOIDS FROM FUMARIACEAE
    BOENTE, JM
    CASTEDO, L
    DELERA, AR
    SAA, JM
    SUAU, R
    VIDAL, MC
    [J]. TETRAHEDRON LETTERS, 1984, 25 (17) : 1829 - 1830
  • [4] Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities
    Boonphong, Surat
    Puangsombat, Pakawan
    Baramee, Apiwat
    Mahidol, Chulabhorn
    Ruchirawat, Somsak
    Kittakoop, Prasat
    [J]. JOURNAL OF NATURAL PRODUCTS, 2007, 70 (05): : 795 - 801
  • [5] Brahmachari, 2019, TOTAL SYNTHESIS BIOA
  • [6] Brahmachari G., 2010, Handbook of pharmaceutical natural products
  • [7] NEW OXIDIZED ISOCULARINE ALKALOIDS FROM SARCOCAPNOS PLANTS
    CAMPELLO, MJ
    CASTEDO, L
    DOMINGUEZ, D
    DELERA, AR
    SAA, JM
    SUAU, R
    TOJO, E
    VIDAL, MC
    [J]. TETRAHEDRON LETTERS, 1984, 25 (51) : 5933 - 5936
  • [8] Novel lactones from Aspergillus versicolor
    Carvalho, MR
    Barbosa, LCD
    de Queiróz, JH
    Howarth, OW
    [J]. TETRAHEDRON LETTERS, 2001, 42 (05) : 809 - 811
  • [9] Previously undescribed benzoxepins with bioactivities against inducible pro-inflammatory cyclooxygenase and lipoxygenase from Rhizophora annamalayana Kathir
    Chakraborty, Kajal
    Raola, Vamshi Krishna
    [J]. NATURAL PRODUCT RESEARCH, 2019, 33 (16) : 2329 - 2337
  • [10] Previously Undescribed Antibacterial Polyketides from Heterotrophic Bacillus amyloliquefaciens Associated with Seaweed Padina gymnospora
    Chakraborty, Kajal
    Thilakan, Bini
    Raola, Vamshi Krishna
    [J]. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2018, 184 (02) : 716 - 732
123456