Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from Cistus ladanifer L.

被引：33
作者：
El Karkouri, Jamila [1 ]
Bouhrim, Mohamed [1 ]
Al Kamaly, Omkulthom Mohamed [2 ]
Mechchate, Hamza [3 ]
Kchibale, Amal [1 ]
Adadi, Imad [1 ]
Amine, Sanae [1 ]
Alaoui Ismaili, Souad [1 ]
Zair, Touriya [1 ]
机构：
[1] Univ Moulay Ismail Meknes, Fac Sci, Lab Mat Innovants & Biothenol Ressources, Res Team Chem Bioact Mol & Environm, BP 11201, Zitoune 50003, Meknes, Morocco
[2] Princess Nourah Bint Abdulrahman Univ, Coll Pharm, Dept Pharmaceut Sci, Riyadh 11564, Saudi Arabia
[3] Univ Sidi Mohamed Ben Abdellah, Fac Sci Dhar El Mahraz, Lab Biotechnol Environm Agrifood & Hlth, POB 1796, Fes 30000, Morocco
来源：
PLANTS-BASEL | 2021年 / 10卷 / 10期
关键词：
C. ladanifer var. maculatus Dun; essential oil; antimicrobial activity; yeast; mold; chemical analysis; AQUEOUS EXTRACT; ANTIMICROBIAL ACTIVITY; CYTOTOXIC ACTIVITY; ETHANOL EXTRACTS; ANTIOXIDANT; MONSPELIENSIS; RESISTANCE; GROWTH;
D O I：
10.3390/plants10102068
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Cistus ladanifer L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out using gas chromatography-mass spectrometry (GC-MS). The antibacterial and antifungal proprieties were tested against four selected bacteria (Staphylococcus aureus, Salmonella Typhi, Escherichia coli, and Acinetobacter baumannii) and nine fungi (Yeasts (Candida tropicalis, Candida glabrata, Candida dubliniensis, Candida sp., Rhodotorula rubra, Cryptococcus neoformans) and molds (Penicillium sp. (P), Fusarium sp. (F), Aspergillus niger (A. niger)), respectively. The essential oil of C. ladanifer demonstrated a powerful antibacterial activity with an inhibition zone of 55 & PLUSMN; 0.22 mm for Staphylococcus aureus, 42 & PLUSMN; 0.11 mm for Escherichia coli, 35 & PLUSMN; 0.27 mm for Acinetobacter baumannii (Full resistant to antibiotics) and 30 & PLUSMN; 0.25 mm for Salmonella Typhi. It also inhibited all tested bacteria at 10 mu L/mL. For the antifungal activity test, C. tropicalis and C. neoformans appeared to be the most sensitive strains to the essential oil with an inhibition zone of 13 mm, followed by R. rubra and Penicillium sp. (12 mm), then C. dubliniensis and C. glabrata (11 mm). The chemical analysis of the essential oil by GC-MS revealed that the major components of the essential oil were viridiflorol (17.64%), pinocarveol (11.02%), bornylacetate (9.38%), and ledol (8.85%). C. ladanifer exhibited a remarkable antimicrobial activity that could be more exploited to develop targeted natural remedies against specific diseases.</p>
引用
收藏
页数：16
相关论文
共 64 条
[51]   Detection of Escherichia coli O157:H7 by multiplex PCR and their characterization by plasmid profiling, antimicrobial resistance, RAPD and PFGE analyses [J].
Radu, S ;
Ling, OW ;
Rusul, G ;
Karim, MIA ;
Nishibuchi, M .
JOURNAL OF MICROBIOLOGICAL METHODS, 2001, 46 (02) :131-139
[52]   Comparison of essential oil composition of two varieties of Cistus ladanifer [J].
Robles, C ;
Bousquet-Mélou, A ;
Garzino, S ;
Bonin, G .
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2003, 31 (03) :339-343
[53]   Antibacterial action of essential oils from Corsica [J].
Rossi, Paul-Georges ;
Berti, Liliane ;
Panighi, Jean ;
Luciani, Anne ;
Maury, Jacques ;
Muselli, Alain ;
de Rocca Serra, Dominique ;
Gonny, Marcelle ;
Bolla, Jean-Michel .
JOURNAL OF ESSENTIAL OIL RESEARCH, 2007, 19 (02) :176-182
[54]   Phytochemical Screening, Antioxidant and Antibacterial Activities of Pollen Extracts from Micromeria fruticosa, Achillea fragrantissima, and Phoenix dactylifera [J].
Sadeq, Omar ;
Mechchate, Hamza ;
Es-safi, Imane ;
Bouhrim, Mohamed ;
Jawhari, Fatima zahra ;
Ouassou, Hayat ;
Kharchoufa, Loubna ;
N. AlZain, Mashail ;
M. Alzamel, Nurah ;
Mohamed Al Kamaly, Omkulthom ;
Bouyahya, Abdelhakim ;
Benoutman, Amina ;
Imtara, Hamada .
PLANTS-BASEL, 2021, 10 (04)
[55]   Monoterpenes and Sesquiterpenes of Essential Oils from Psidium Species and Their Biological Properties [J].
Silva, Renan Campos e ;
da Costa, Jamile S. ;
de Figueiredo, Raphael O. ;
Setzer, William N. ;
da Silva, Joyce Kelly R. ;
Maia, Jose Guilherme S. ;
Figueiredo, Pablo Luis B. .
MOLECULES, 2021, 26 (04)
[56]   Cytotoxic activity of ethanol extracts of in vitro grown Cistus creticus subsp creticus L. on human cancer cell lines [J].
Skoric, Marijana ;
Todorovic, Sladana ;
Gligorijevic, Nevenka ;
Jankovic, Radmila ;
Zivkovic, Suzana ;
Ristic, Mihailo ;
Radulovic, Sinisa .
INDUSTRIAL CROPS AND PRODUCTS, 2012, 38 :153-159
[57]   Inhibition of mouth skeletal muscle relaxation by flavonoids of Cistus ladanifer L.:: A plant defense mechanism against herbivores [J].
Sosa, T ;
Chaves, N ;
Alias, JC ;
Escudero, JC ;
Henao, F ;
Gutiérrez-Merino, C .
JOURNAL OF CHEMICAL ECOLOGY, 2004, 30 (06) :1087-1101
[58]   REPRODUCTIVE-BIOLOGY OF CISTUS-LADANIFER (CISTACEAE) [J].
TALAVERA, S ;
GIBBS, PE ;
HERRERA, J .
PLANT SYSTEMATICS AND EVOLUTION, 1993, 186 (3-4) :123-134
[59]   Phytotoxic Effects and Mechanism of Action of Essential Oils and Terpenoids [J].
Verdeguer, Mercedes ;
Sanchez-Moreiras, Adela M. ;
Araniti, Fabrizio .
PLANTS-BASEL, 2020, 9 (11) :1-48
[60]   Chemical composition and herbicidal activity of the essential oil from a Cistus ladanifer L. population from Spain [J].
Verdeguer, Mercedes ;
Amparo Blazquez, M. ;
Boira, Herminio .
NATURAL PRODUCT RESEARCH, 2012, 26 (17) :1602-1609
1234567