Microbial and enzymatic methods for the removal of caffeine

被引：93

作者：

Gokulakrishnan, S ^{[1
]}

Chandraraj, K ^{[1
]}

Gummadi, SN ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Biotechnol, Madras 600036, Tamil Nadu, India

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 2005年 / 37卷 / 02期

关键词：

caffeine; methyl xanthines; demethylase; caffeine oxidase; decaffeination; microbial degradation; metabolism;

D O I：

10.1016/j.enzmictec.2005.03.004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Caffeine is a purine alkaloid and is a major constituent of coffee, tea and other beverages. It acts as a central nervous system stimulant and also has negative withdrawal effects. Decaffeinated beverages are being used to overcome its negative effects. Decaffeination is done by different methods like solvent, water and super critical fluid extraction. These methods apart from being non-specific are expensive and involve the usage of toxic organic solvents. Development of a process involving an enzymatic (specific) degradation of caffeine to non-toxic compound is necessary to solve the problems of chemical extraction of caffeine in food products as well as treating the caffeine containing waste products. The different microbial and enzymatic methods of caffeine removal are discussed in this review. The literature revealed that major caffeine degrading strains belong to Pseudomonas and Aspergillus. Though the enzymes involved in degradation of caffeine by microorganisms are known, in vitro enzymatic studies for caffeine degradation is not yet reported. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：225 / 232

页数：8

共 83 条

[1] MICROBIAL-PRODUCTION OF THEOBROMINE FROM CAFFEINE [J].

ASANO, Y ;

KOMEDA, T ;

YAMADA, H .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1993, 57 (08) :1286-1289

[2] ENZYMES INVOLVED IN THEOBROMINE PRODUCTION FROM CAFFEINE BY PSEUDOMONAS-PUTIDA NO-352 [J].

ASANO, Y ;

KOMEDA, T ;

YAMADA, H .

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 1994, 58 (12) :2303-2304

[3] Catabolism of caffeine and related purine alkaloids in leaves of Coffea arabica L [J].

Ashihara, H ;

Monteiro, AM ;

Moritz, T ;

Gillies, FM ;

Crozier, A .

PLANTA, 1996, 198 (03) :334-339

[4] Metabolism of caffeine and related purine alkaloids in leaves of tea (Camellia sinensis L) [J].

Ashihara, H ;

Gillies, FM ;

Crozier, A .

PLANT AND CELL PHYSIOLOGY, 1997, 38 (04) :413-419

[5]

Avallone S, 2001, CURR MICROBIOL, V42, P252, DOI 10.1007/s002840010213

[6] METABOLISM OF CAFFEINE BY A PSEUDOMONAS-PUTIDA STRAIN [J].

BLECHER, R ;

LINGENS, F .

HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1977, 358 (07) :807-817

[7] Caffeine: also a fungal metabolite [J].

Bogo, A ;

Mantle, PG .

PHYTOCHEMISTRY, 2000, 54 (08) :937-939

[8] Biological detoxification of coffee husk by filamentous fungi using a solid state fermentation system [J].

Brand, D ;

Pandey, A ;

Roussos, S ;

Soccol, CR .

ENZYME AND MICROBIAL TECHNOLOGY, 2000, 27 (1-2) :127-133

[9] Relationship between coffee husk caffeine degradation and respiration of Aspergillus sp LPBx in solid-state fermentation [J].

Brand, D ;

Pandey, A ;

Rodriguez-Leon, JA ;

Soccol, CR .

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2002, 102 (1-6) :169-177

[10] Packed bed column fermenter and kinetic modeling for upgrading the nutritional quality of coffee husk in solid-state fermentation [J].

Brand, D ;

Pandey, A ;

Rodriguez-Leon, JA ;

Roussos, S ;

Brand, I ;

Soccol, CR .

BIOTECHNOLOGY PROGRESS, 2001, 17 (06) :1065-1070

← 1 2 3 4 5 6 7 8 9 →