New secondary metabolites from the endophytic fungus Fusarium sp HP-2 isolated from "Qi-Nan" agarwood

被引：18
|
作者：
Xiao, Wen-Jie [1 ]
Chen, Hui-Qin [1 ]
Wang, Hao [1 ]
Cai, Cai-Hong [1 ]
Mei, Wen-Li [1 ]
Dai, Hao-Fu [1 ]
机构：
[1] Chinese Acad Trop Agr Sci, Inst Trop Biosci & Biotechnol, Minist Agr, Key Lab Biol & Genet Resources Trop Crops, Haikou 571101, Hainan, Peoples R China
来源：
FITOTERAPIA | 2018年 / 130卷
关键词：
Qi-Nan" agarwood; Endophytic fungus; Fusarium sp; Furan derivative; Naphthalenone derivative; AQUILARIA-SINENSIS; GENES;
D O I：
10.1016/j.fitote.2018.08.008
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
A novel pyrone derivative (1) bearing two fused five-member rings, together with two new naphthalenone derivatives (2, 3), as well as two known compounds (4, 5) were obtained from the endophytic fungus Fusarium sp. HP-2, which was isolated from "Qi-Nan" agarwood. The structures of the new compounds were elucidated by analysis of 1D and 2D NMR, and by HRESIMS spectra, as well as by comparison with the literature. Bioactivity results indicated that compound 3 showed weak acetylcholinesterase inhibitory activity.
引用
收藏
页码：180 / 183
页数：4
相关论文
共 50 条
  • [41] Secondary Metabolites of the Endophytic Fungus Chaetomium globosum Isolated From Coptis chinensis
    Ji, Jia-Cheng
    Wei, Pan-Pan
    Han, Xiao-Yang
    Li, Zheng-Hui
    Ai, Hong-Lian
    Lei, Xin-Xiang
    NATURAL PRODUCT COMMUNICATIONS, 2021, 16 (09)
  • [42] Mediating Effect of Bio-Organic Fertilizer on the Physiological Characteristics of "Qi-Nan" Agarwood from Aquilaria sinensis (Lour.)
    Huang, Jingyue
    Zhao, Zhang
    Bai, Tiandao
    Xiong, Junfei
    Li, Yingjian
    Wei, Penglian
    Fu, Yunlin
    FORESTS, 2023, 14 (04):
  • [43] Bioactive Secondary Metabolites from Phomopsis sp., an Endophytic Fungus from Senna spectabilis
    Chapla, Vanessa Mara
    Zeraik, Maria Luiza
    Ximenes, Valdecir F.
    Zanardi, Lisineia Maria
    Lopes, Marcia N.
    Cavalheiro, Alberto Jose
    Silva, Dulce Helena S.
    Young, Maria Claudia M.
    da Fonseca, Luiz Marcos
    Bolzani, Vanderlan S.
    Araujo, Angela Regina
    MOLECULES, 2014, 19 (05): : 6597 - 6608
  • [44] New and antioxicant secondary metabolites from the endophytic fungus Nigrospora sphaerica
    Metwaly, A.
    Kadry, H.
    El-Hela, A.
    Elsalam, A.
    Ross, S.
    PLANTA MEDICA, 2014, 80 (10) : 770 - 770
  • [45] Alkaloids isolated from the endophytic fungus Fusarium concentricum
    Zhang, Xi-Lin
    Lu, Bing-Guo
    Bai, Jian
    Li, Ning
    NATURAL PRODUCT RESEARCH, 2024, 38 (09) : 1517 - 1523
  • [46] Discovery of antifungal secondary metabolites from an intestinal fungus Fusarium sp.
    Zhang, Mingkai
    Chen, Baosong
    Dai, Huanqin
    Sun, Jingzu
    Liu, Hongwei
    Han, Junjie
    JOURNAL OF ANTIBIOTICS, 2024, 77 (03): : 163 - 169
  • [47] Discovery of antifungal secondary metabolites from an intestinal fungus Fusarium sp.
    Mingkai Zhang
    Baosong Chen
    Huanqin Dai
    Jingzu Sun
    Hongwei Liu
    Junjie Han
    The Journal of Antibiotics, 2024, 77 : 193 - 198
  • [48] New secondary metabolites from the mangrove endophytic fungus Aspergillus versicolor
    Elsbaey, Marva
    Tanaka, Chiaki
    Miyamoto, Tomofumi
    PHYTOCHEMISTRY LETTERS, 2019, 32 : 70 - 76
  • [49] New secondary metabolites from the marine endophytic fungus Apiospora montagnei
    Klemke, C
    Kehraus, S
    Wright, AD
    König, GM
    JOURNAL OF NATURAL PRODUCTS, 2004, 67 (06): : 1058 - 1063
  • [50] Metabolites from the endophytic fungus Cylindrocarpon sp isolated from tropical plant Sapium ellipticum
    Kamdem, Ramsay S. T.
    Pascal, Wafo
    Rehberg, Nidja
    van Geelen, Lasse
    Hoefert, Simon-Patrick
    Knedel, Tim-Oliver
    Janiak, Christoph
    Sureechatchaiyan, Parichat
    Kassack, Matthias U.
    Lin, Wenhan
    Kalscheuer, Rainer
    Liu, Zhen
    Proksch, Peter
    FITOTERAPIA, 2018, 128 : 175 - 179
12345