Sequential C-S and S-N Coupling Approach to Sulfonamides

被引：63

作者：

Chen, Kai ^{[1
]}

Chen, Wei ^{[1
]}

Han, Bing ^{[1
]}

Chen, Wanzhi ^{[1
]}

Liu, Miaochang ^{[2
]}

Wu, Huayue ^{[2
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

[2] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325027, Peoples R China

来源：

ORGANIC LETTERS | 2020年 / 22卷 / 05期

关键词：

ONE-POT SYNTHESIS; SULFUR-DIOXIDE; ARYLSULFONYL CHLORIDES; BORONIC ACIDS; NITROARENES; DABSO; 3-COMPONENT; SULFONES; HALIDES; ARYL;

D O I：

10.1021/acs.orglett.0c00183

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot three-component reaction involving nitroarenes, (hetero)arylboronic acids, and potassium pyrosulfite leading to sulfonamides was described. A broad range of sulfonamides bearing different reactive functional groups were obtained in good to excellent yields through sequential C-S and S-N coupling that does not require metal catalysts.

引用

页码：1841 / 1845

页数：5

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