Assessment of Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratios in Patients with Temporal Lobe Epilepsy

被引:1
作者
Baran, Oguz [1 ]
Korkmaz, Taha Sukru [2 ]
Kemerdere, Rahsan [2 ]
Akcil, Eren Fatma [3 ]
Yeni, Seher Naz [4 ]
Uzan, Mustafa [2 ]
Tanriverdi, Taner [2 ]
机构
[1] Haseki Training & Res Hosp, Dept Neurosurg, Istanbul, Turkey
[2] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Neurosurg, Istanbul, Turkey
[3] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Anesthesiol & Reanimat, Istanbul, Turkey
[4] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Neurol, Istanbul, Turkey
来源
EPILEPSI | 2020年 / 26卷 / 01期
关键词
Epilepsy; inflammation; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio; temporal lobe epilepsy; CELL DISTRIBUTION WIDTH; INFLAMMATION; PREDICTOR;
D O I
10.14744/epilepsi.2019.65902
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives:This retrospective study aims to evaluate preoperative levels of neutrophil to lymphocyte (NLR) and platelet to lymphocyte ratios (PLR) in patients with temporal lobe epilepsy and to compare with controls. Methods: Patients and control groups consisted of 36 and 35 subjects, respectively, and routine complete blood count was obtained for NLR and PLR analysis. Results: The two ratios were higher in patients, but differences were not significant (p>0.05). Disease severity, such as high seizure frequency, duration of seizure, and presence of the history of febrile seizure, was not significantly correlated either with NLR or PLR. Findings did not provide evidence of usefulness for discrimination between temporal lobe epilepsy and controls. Conclusion: Further prospective studies, including a larger sample size, should be conductedto have more valuable results for interpretation.
引用
收藏
页码:30 / 34
页数:5
相关论文
共 13 条
[1]  
Ahmedov ML, 2017, WORLD NEUROSURG, V106, P46, DOI [10.1016/j.WNEU.2017.06.137, 10.1016/j.wneu.2017.06.137]
[2]   Association of preoperative levels of selected blood inflammatory markers with prognosis in gliomas [J].
Auezova, Raushan ;
Ryskeldiev, Nurzhan ;
Doskaliyev, Aidos ;
Kuanyshev, Yerbol ;
Zhetpisbaev, Berik ;
Aldiyarova, Nurgul ;
Ivanova, Natalia ;
Akshulakov, Serik ;
Auezova, Lizette .
ONCOTARGETS AND THERAPY, 2016, 9 :6111-6117
[3]  
Goksugur SB, 2014, EUR REV MED PHARMACO, V18, P3380
[4]   The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis [J].
Mallucci, Giulia ;
Peruzzotti-Jametti, Luca ;
Bernstock, Joshua D. ;
Pluchino, Stefano .
PROGRESS IN NEUROBIOLOGY, 2015, 127 :1-22
[5]   Elevated preoperative neutrophil-to-lymphocyte ratio as a predictor of worse survival after resection in patients with brain metastasis [J].
Mitsuya, Koichi ;
Nakasu, Yoko ;
Kurakane, Takeshi ;
Hayashi, Nakamasa ;
Harada, Hideyuki ;
Nozaki, Kazuhiko .
JOURNAL OF NEUROSURGERY, 2017, 127 (02) :433-437
[6]  
Olivier A, 2012, TECHNIQUES IN EPILEPSY SURGERY: THE MNI APPROACH, P1, DOI 10.1017/CBO9781139021951
[7]   Changes in serum albumin levels and neutrophil-lymphocyte ratio in patients with convulsive status epilepticus [J].
Ozdemir, Hasan H. ;
Akil, Esref ;
Acar, Abdullah ;
Tamam, Yusuf ;
Varol, Sefer ;
Cevik, Mehmet Ugur ;
Arikanoglu, Adalet .
INTERNATIONAL JOURNAL OF NEUROSCIENCE, 2017, 127 (05) :417-420
[8]   Is epilepsy a progressive disorder?: Prospects for new therapeutic approaches in temporal-lobe epilepsy [J].
Pitkänen, A ;
Sutula, TP .
LANCET NEUROLOGY, 2002, 1 (03) :173-181
[9]   Lymphocyte infiltration of neocortex and hippocampus after a single brief seizure in mice [J].
Silverberg, J. ;
Ginsburg, D. ;
Orman, R. ;
Amassian, V. ;
Durkin, H. G. ;
Stewart, M. .
BRAIN BEHAVIOR AND IMMUNITY, 2010, 24 (02) :263-272
[10]   The role of inflammation in epilepsy [J].
Vezzani, Annamaria ;
French, Jacqueline ;
Bartfai, Tamas ;
Baram, Tallie Z. .
NATURE REVIEWS NEUROLOGY, 2011, 7 (01) :31-40