Brainstem-Sparing Craniospinal Irradiation Delivered With Pencil Beam Scanning Proton Therapy

被引：2

作者：

Hill-Kayser, Christine ^{[1
]}

Kirk, Maura ^{[1
]}

机构：

[1] Univ Penn, Perelman Sch Med, Dept Radiat Oncol, Philadelphia, PA 19104 USA

来源：

PEDIATRIC BLOOD & CANCER | 2015年 / 62卷 / 04期

关键词：

craniospinal irradiation; ependymoma; pencil beam scanning; proton therapy; TREATMENT UNCERTAINTIES; RADIOTHERAPY; SENSITIVITY; OUTCOMES;

D O I：

10.1002/pbc.25378

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Delivery of craniospinal irradiation (CSI) is a curative approach to recurrent ependymoma, but is associated with risks from re-irradiation, particularly of the brainstem. Pencil beam scanning proton therapy allows delivery of CSI with sparing of normal tissues. Here, we describe a case of brainstem-sparing CSI that resulted in excellent coverage of the craniospinal axis with minimal radiation to brainstem. This is a novel concept that compares favorably to previously described methods using x-rays that may result in underdosing of surrounding tissues in effort to spare brainstem. Pediatr Blood Cancer 2015;62:718-720. (c) 2015 Wiley Periodicals, Inc.

引用

页码：718 / 720

页数：3

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