Randomized, double-blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease

被引：52
|
作者：
Mizuno, Y
Yanagisawa, N
Kuno, S
Yamamoto, M
Hasegawa, K
Origasa, H
Kowa, H
机构：
[1] Juntendo Univ, Sch Med, Dept Neurol, Bunkyo Ku, Tokyo 1138421, Japan
[2] Kanto Rosai Hosp, Kawasaki, Kanagawa, Japan
[3] Natl Utano Hosp, Ctr Neurol Dis, Clin Res Sect, Kyoto, Japan
[4] Kagawa Prefectural Cent Hosp, Dept Neurol, Takamatsu, Kagawa, Japan
[5] Sagamihara Natl Hosp, Dept Neurol, Sagamihara, Kanagawa, Japan
[6] Toyama Med & Pharmaceut Univ, Fac Med, Div Biostat, Toyama, Japan
[7] Kitasato Univ, Tokyo, Japan
来源：
MOVEMENT DISORDERS | 2003年 / 18卷 / 10期
关键词：
Parkinson's disease; pramipexole; bromocriptine; levodopa; drug comparison; randomized controlled trial (RCT);
D O I：
10.1002/mds.10508
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We compared the efficacy and safety of pramipexole (PPX) with placebo in the treatment of advanced Parkinson's disease (PD) as an adjunct to levodopa. A bromocriptine (1311) group was included to enable determination of the noninferiority of PPX relative to 1311 as the standard treatment. (C) 2003 Movement Disorder Society.
引用
收藏
页码：1149 / 1156
页数：8
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