Abdominal adiposity, insulin resistance, hypertension and urinary sodium in obese adolescents

被引:0
作者
Susana Lopez, Miryan
Noemi Maskin de Jensen, Alicia
Nora Mir, Claudia
Esther Ibanez de Pianesi, Maria
Alejandra Manulak, Maria
机构
[1] Univ Nacl Misiones, Fac Ciencias Exactas Quim Nat, Posadas, Misiones, Argentina
[2] Hosp Prov Pediat Dr Fernando Barreyro, Posadas, Misiones, Argentina
来源
ACTA BIOQUIMICA CLINICA LATINOAMERICANA | 2014年 / 48卷 / 03期
关键词
abdominal adiposity; insulin resistance; hypertension; urinary sodium excretion; obese adolescents; HIGH BLOOD-PRESSURE; METABOLIC SYNDROME; WAIST CIRCUMFERENCE; CARDIOVASCULAR RISK; CHILDREN; PREVALENCE; ASSOCIATION; OVERWEIGHT; POPULATION; NUTRITION;
D O I
暂无
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
The aim of this study was to assess abdominal adiposity relationship with insulin resistance, high blood pressure and urinary sodium excretion in an obese adolescent population. A descriptive cross sectional study that included 107 obese teenagers from 10 to 14 years of age without any dietary restriction was performed during 2011 and 2012 at the Pediatric Hospital, in Posadas, Misiones. Abdominal obesity was defined as: waist perimeter >= p90, hypertension: systolic and/or diastolic pressure >= p95 and prehypertension >= p90 and <p95 adjusted for gender, age and height. Cut value to insulin resistance was HOMA-IR >= 3. Sodium was measured in 24 h urine (Na-ur) by selective ion electrode and insulin by chemiluminiscence. A total of 93% of the obese population showed high waist circumference, 49% insulin resistance, 21% severe obesity (IMC score z >= 3) and 23% showed hypertension/prehypertension. Waist circumference correlation was significant and positive with arterial systolic pressure, arterial diastolic pressure and insulin resistance. It resulted significantly negative to sodium urinary excretion. The obese teenagers who had more abdominal fat showed higher systolic pressure, diastolic pressure values, insulin resistance and odd sodium homeostasis with lower urinary excretion of the previously mentioned ion.
引用
收藏
页码:301 / 310
页数:10
相关论文
共 65 条
[1]  
Garcia EA, 2011, ACTA BIOQUIM CLIN L, V45, P423
[2]   Hypertension and obesity [J].
Aneja, A ;
El-Atat, F ;
McFarlane, S ;
Sowers, JR .
RECENT PROGRESS IN HORMONE RESEARCH, VOL 59: CARDIOVASCULAR ENDOCRINOLOGY & OBESITY, 2004, 59 :169-205
[3]  
[Anonymous], 2005, Arch. argent. pediatr., V103, P262
[4]   Relationship of Obesity with High Blood Pressure in Children and Adolescents [J].
Barbosa de Souza, Maria Goretti ;
Rivera, Ivan Romero ;
Mendonca da Silva, Maria Alayde ;
Camargo Carvalho, Antonio Carlos .
ARQUIVOS BRASILEIROS DE CARDIOLOGIA, 2010, 94 (06) :714-719
[5]   The role of obesity in the pathogenesis of hypertension [J].
Bogaert, Yolanda E. ;
Linas, Stuart .
NATURE CLINICAL PRACTICE NEPHROLOGY, 2009, 5 (02) :101-111
[6]   Pediatric Approach to Hypertension [J].
Brady, Tammy M. ;
Feld, Leonard G. .
SEMINARS IN NEPHROLOGY, 2009, 29 (04) :379-388
[7]   Sexual dimorphism of body composition and insulin sensitivity across pubertal development in obese Caucasian subjects [J].
Brufani, Claudia ;
Tozzi, Alberto ;
Fintini, Danilo ;
Ciampalini, Paolo ;
Grossi, Armando ;
Fiori, Rossana ;
Kiepe, Daniela ;
Manco, Melania ;
Schiaffini, Riccardo ;
Porzio, Ottavia ;
Cappa, Marco ;
Barbetti, Fabrizio .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2009, 160 (05) :769-775
[8]  
Burrows R, 2008, ARCH LATIN NEFR RED, V8, P1
[9]   Endothelial dysfunction in obesity and insulin resistance: A road to diabetes and heart disease [J].
Caballero, AE .
OBESITY RESEARCH, 2003, 11 (11) :1278-1289
[10]  
Chaila MZ, 2012, Rev. argent. endocrinol. metab., V49, P103