Effect of surfactants on peroxidase activity. I. Effect of anionic surfactants

被引：0
|
作者：
Davletshin, AI
Egorov, VV
Zubov, VP
机构：
[1] Skryabin State Acad Vet Med & Biotechnol, Moscow 109472, Russia
[2] Russian Acad Sci, Shemyakin Ovchinnikov Inst Bioorgan Chem, Moscow 117871, Russia
来源：
BIOORGANICHESKAYA KHIMIYA | 1998年 / 24卷 / 06期
关键词：
horseradish peroxidase; anionic surfactants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The effect of various anionic surfactants on the initial rate of 5-aminosalicylic acid peroxidation with horseradish peroxidase was studied. With increasing surfactant concentration, this rate first decreased, then increased, and again decreased. We conclude that these changes were due to an inhibition of the enzyme, a subsequent change in the enzyme conformation accompanied by the enhanced accessibility of its active site to the substrate, and the final protein denaturation, respectively.
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页码：426 / 429
页数：4
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