Synthesis of the antibiotically active part of agrocin 84

被引：11

作者：

Filippov, D ^{[1
]}

Timmers, CM ^{[1
]}

Roerdink, AR ^{[1
]}

van der Marel, GA ^{[1
]}

van Boom, JH ^{[1
]}

机构：

[1] Leiden Univ, Leiden Inst Chem, Gorlaeus Labs, NL-2300 RA Leiden, Netherlands

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 27期

关键词：

D O I：

10.1016/S0040-4039(98)00888-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phosphitylation of bis-O-silylated threo-2,3-dihydroxy-4-methylpentanamide and condensation of the resulting N-acylphosphorodiamidite with 2'-O-acetyl-3'-deoxyarabinoadenosine led, after oxidation and deprotection, to the isolation of the title compound. (C) 1998 Elsevier Science Ltd. Ail rights reserved.

引用

页码：4891 / 4894

页数：4

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