Hirsutellones A-E, antimycobacterial alkaloids from the insect pathogenic fungus Hirsutella nivea BCC 2594

被引:173
作者
Isaka, M
Rugseree, N
Maithip, P
Kongsaeree, P
Prabpai, S
Thebtaranonth, Y
机构
[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, Pathum Thani 12120, Thailand
[2] Mahidol Univ, Fac Sci, Dept Chem, Bangkok 10400, Thailand
关键词
Hirsutella nivea; antimycobacterial activity; insect pathogenic fungi;
D O I
10.1016/j.tet.2005.03.099
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Five new alkaloids. hirsutellones A-E, were isolated front the insect pathogenic fungus Hirsutella nivea BCC 2594. Their structures were elucidated by spectroscopic analysis and X-ray crystallography. Hirsutellones displayed significant growth inhibitory activity against Mycobacterium tuberculosis H37Ra. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:5577 / 5583
页数:7
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