The core of hepatitis C virus pathogenesis

被引：21
作者：
Kao, C. Cheng [1 ]
Yi, Guanghui [1 ]
Huang, Hsuan-Cheng [2 ]
机构：
[1] Indiana Univ, Dept Mol & Cellular Biochem, Bloomington, IN 47405 USA
[2] Natl Yang Ming Univ, Inst Biomed Informat, Taipei 11221, Taiwan
来源：
CURRENT OPINION IN VIROLOGY | 2016年 / 17卷
关键词：
INTERFERON-STIMULATED GENES; ACTING RNA ELEMENTS; HEPATOCELLULAR-CARCINOMA; T-CELLS; PROTEIN-INTERACTION; MEDIATED APOPTOSIS; NATURAL-HISTORY; UP-REGULATION; HCV; EXPRESSION;
D O I：
10.1016/j.coviro.2016.01.009
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Capsid proteins form protective shells around viral genomes and mediate viral entry. However, many capsid proteins have additional and important roles for virus infection and in modulating cellular response to infection, with important consequences on pathogenesis. Infection by the Hepatitis C virus (HCV) can lead to liver steatosis, cirrhosis, and hepatocellular carcinoma. Herein, we focus on the role in pathogenesis of Core, the capsid protein of the HCV.
引用
收藏
页码：66 / 73
页数：8
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