The purpose of this study was to explore the teaching approaches using a blended learning incorporated with the IATA Rules and Regulations course content. In the 2019, action research was conducted in Airline Business classes of International College, Suan Sunandha Rajabhat University, Thailand. In the blended learning, the researcher created online lessons of his lectures and the students viewed them prior to attending class. The International Air Transport Association is a trade association of the world's airlines. That is consisting of 290 airlines, primarily major carriers, representing 117 countries, the IATA's member airlines account for carrying approximately 82% of total of air traffic in the world. Thailand is now on the path of industrialization, the need of new innovation and technology product is a must the reach this goal. A new method of learning that is called blended learning has been introduces for this IATA class to enable student benefit from learning. In the blended learning, the researcher created online lessons of his lectures and the students viewed them prior to attending class. Students worked on problem-solving activities in their classrooms. The students used smart phones, tablets & computer. The research findings indicated that the blended learning of instruction was new teaching strategy that moved the lecture on outside classroom via technology and brought assignments/exercises of IATA contents and concepts inside the classroom via learning activities. The research findings shown the students engagement in the blended learning were higher than the using traditional classroom. Based on the students' interviews they revealed that using blended learning incorporated with smartphone and students group activities they were able to make learning fun and challenging.