pH-Dependent fluorescence of [La(OH)2]+[ARS]- hybrid nanoparticles for intracellular pH-sensing

被引：4
作者：
Sabljo, Kristina [1 ]
Napp, Joanna [2 ,3 ]
Alves, Frauke [2 ,3 ]
Feldmann, Claus [1 ]
机构：
[1] Karlsruhe Inst Technol KIT, Inst Inorgan Chem, Engesserstr 15, D-76131 Karlsruhe, Germany
[2] Univ Med Ctr Goettingen UMG, Inst Diagnost & Intervent Radiol, Robert Koch Str 40, D-37075 Gottingen, Germany
[3] Max Planck Inst Multidisciplinary Sci, Translat Mol Imaging, Hermann Rein Str 3, D-37075 Gottingen, Germany
来源：
CHEMICAL COMMUNICATIONS | 2022年 / 58卷 / 67期
关键词：
ALIZARIN RED S; DESIGN; PRINCIPLES; DELIVERY; SENSORS; CELLS;
D O I：
10.1039/d2cc01507b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Saline inorganic-organic hybrid nanoparticles (IOH-NPs) [La(OH)(2)](+)[ARS](-) (ARS: alizarin red S) are prepared in water as a new compound (particle size: 47 +/- 7 nm, ARS load: 65 wt%). The IOH-NPs not only show a pH-dependent absorption colour but also a pH-dependent fluorescence with green emission at pH 5.0-9.0 and red emission at pH < 4.5. According to first in vitro studies, the pH-dependend fluorescence can be used to monitor nanoparticle internalization in cells as well as the respective intracellular pH.
引用
收藏
页码：9417 / 9420
页数：4
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