Evaluation of Antioxidant Capacity and Synergistic Associations of Quinonemethide Triterpenes and Phenolic Substances from Maytenus ilicifolia (Celastraceae)

被引：36

作者：

Formenton Macedo dos Santos, Vania Aparecida de Freitas ^{[1
]}

dos Santos, Daniela Pereira ^{[2
]}

Castro-Gamboa, Ian ^{[1
]}

Boldrin Zanoni, Maria Valnice ^{[2
]}

Furlan, Maysa ^{[1
]}

机构：

[1] Univ Estadual Paulista, Inst Quim, Nucleo Bioensaios Biossintese & Ecofisiol Prod Na, Dept Quim Organ, BR-14801970 Araraquara, SP, Brazil

[2] Univ Estadual Paulista, Inst Quim, Dept Quim Analit, BR-14801970 Araraquara, SP, Brazil

来源：

MOLECULES | 2010年 / 15卷 / 10期

基金：

巴西圣保罗研究基金会;

关键词：

antioxidant; high-performance liquid chromatography coupled with; electrochemical detection (HPLC-EICD); cyclic voltammetry (CV); quinonemethide; flavonoid; SESQUITERPENE PYRIDINE ALKALOIDS; ELECTROCHEMICAL DETECTION; FLAVONOID GLYCOSIDES; AQUIFOLIUM; EXTRACTS; HPLC; LEAVES; METHIDE;

D O I：

10.3390/molecules15106956

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This work describes the isolation of the secondary metabolites identified as the quinonemethides maytenin (1) and pristimerin (2) from Maytenus ilicifolia extracts obtained from root barks of adult plants and roots of seedlings and their quantification by high performance liquid chromatography coupled to a diode array detector. The electrochemical profiles obtained from cyclic voltammetry and a coulometric detector coupled to high-performance liquid chromatography contributed to the evaluation of their antioxidant capacity. The antioxidant properties of individual components and the crude extracts of the root barks of Maytenus ilicifolia were compared and the possible synergistic associations of quinonemethide triterpenes and phenolic substances were investigated by using rutin as a model phenolic compound.

引用

页码：6956 / 6973

页数：18

共 58 条

[51] "Review of Maytenus ilicifolia Mart. ex Reissek, Celastraceae. Contribution to the studies of pharmacological properties". [J].

Santos-Oliveira, Ralph ;

Coulaud-Cunha, Simone ;

Colaco, Waldeciro .

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, 2009, 19 (2B) :650-659

[52] Application of HPLC with electrochemical detection for the determination of low levels of antioxidants [J].

Skrinjar, Maja ;

Kolar, Majda Hadolin ;

Jelsek, Natasa ;

Hras, Andreja Rizner ;

Bezjak, Miran ;

Knez, Zeljko .

JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 2007, 20 (07) :539-545

[53] Contents and antioxidant capacity of limonin and nomilin in different tissues of citrus fruit of four cultivars during fruit growth and maturation [J].

Sun, CD ;

Chen, KS ;

Chen, Y ;

Chen, QJ .

FOOD CHEMISTRY, 2005, 93 (04) :599-605

[54] Identification of flavonols in leaves of Maytenus ilicifolia and M-aquifolium (Celastraceae) by LC/UV/MS analysis [J].

Tiberti, Luciana A. ;

Yariwake, Janete H. ;

Ndjoko, Karine ;

Hostettmann, Kurt .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 846 (1-2) :378-384

[55] Structural aspects of antioxidant activity of flavonoids [J].

vanAcker, SABE ;

vandenBerg, DJ ;

Tromp, MNJL ;

Griffioen, DH ;

VanBennekom, WP ;

VanderVijgh, WJF ;

Bast, A .

FREE RADICAL BIOLOGY AND MEDICINE, 1996, 20 (03) :331-342

[56] Antioxidant activity of Maytenus ilicifolia root bark [J].

Vellosa, JCR ;

Khalil, NM ;

Formenton, VAF ;

Ximenes, VF ;

Fonseca, LM ;

Furlan, M ;

Brunetti, IL ;

Oliveira, OMMF .

FITOTERAPIA, 2006, 77 (03) :243-244

[57]

Vellosa José Carlos Rebuglio, 2007, Rev. Bras. Cienc. Farm., V43, P447, DOI 10.1590/S1516-93322007000300013

[58] Isolation and structure elucidation of two new flavonoid glycosides from the infusion of Maytenus aquifolium leaves.: Evaluation of the antiulcer activity of the infusion [J].

Vilegas, W ;

Sanommiya, M ;

Rastrelli, L ;

Pizza, C .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1999, 47 (02) :403-406

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