Evaluation of Antioxidant Capacity and Synergistic Associations of Quinonemethide Triterpenes and Phenolic Substances from Maytenus ilicifolia (Celastraceae)

被引:36
作者
Formenton Macedo dos Santos, Vania Aparecida de Freitas [1 ]
dos Santos, Daniela Pereira [2 ]
Castro-Gamboa, Ian [1 ]
Boldrin Zanoni, Maria Valnice [2 ]
Furlan, Maysa [1 ]
机构
[1] Univ Estadual Paulista, Inst Quim, Nucleo Bioensaios Biossintese & Ecofisiol Prod Na, Dept Quim Organ, BR-14801970 Araraquara, SP, Brazil
[2] Univ Estadual Paulista, Inst Quim, Dept Quim Analit, BR-14801970 Araraquara, SP, Brazil
来源
MOLECULES | 2010年 / 15卷 / 10期
基金
巴西圣保罗研究基金会;
关键词
antioxidant; high-performance liquid chromatography coupled with; electrochemical detection (HPLC-EICD); cyclic voltammetry (CV); quinonemethide; flavonoid; SESQUITERPENE PYRIDINE ALKALOIDS; ELECTROCHEMICAL DETECTION; FLAVONOID GLYCOSIDES; AQUIFOLIUM; EXTRACTS; HPLC; LEAVES; METHIDE;
D O I
10.3390/molecules15106956
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This work describes the isolation of the secondary metabolites identified as the quinonemethides maytenin (1) and pristimerin (2) from Maytenus ilicifolia extracts obtained from root barks of adult plants and roots of seedlings and their quantification by high performance liquid chromatography coupled to a diode array detector. The electrochemical profiles obtained from cyclic voltammetry and a coulometric detector coupled to high-performance liquid chromatography contributed to the evaluation of their antioxidant capacity. The antioxidant properties of individual components and the crude extracts of the root barks of Maytenus ilicifolia were compared and the possible synergistic associations of quinonemethide triterpenes and phenolic substances were investigated by using rutin as a model phenolic compound.
引用
收藏
页码:6956 / 6973
页数:18
相关论文
共 58 条
[41]   Natural antioxidants from residual sources [J].
Moure, A ;
Cruz, JM ;
Franco, D ;
Domínguez, JM ;
Sineiro, J ;
Domínguez, H ;
Núñez, MJ ;
Parajó, JC .
FOOD CHEMISTRY, 2001, 72 (02) :145-171
[42]   ANTITUMOR AGENTS .73. ANTITUMOR TRITERPENES OF MAYTENUS-DIVERSIFOLIA [J].
NOZAKI, H ;
SUZUKI, H ;
HIRAYAMA, T ;
KASAI, R ;
WU, RY ;
LEE, KH .
PHYTOCHEMISTRY, 1986, 25 (02) :479-485
[43]   Assessment of the TEAC method for determining the antioxidant capacity of synthetic red food colorants [J].
Obón, JM ;
Castellar, MR ;
Cascales, JA ;
Fernández-López, JA .
FOOD RESEARCH INTERNATIONAL, 2005, 38 (8-9) :843-845
[44]   ANTIOXIDANT ACTIVITY OF EXTRACTS AND CONDENSED TANNINS FROM LEAVES OF Maytenus ilicifolia MART. ex REISS. [J].
Pessuto, Monica Bordin ;
da Costa, Isis Casemiro ;
de Souza, Angelita Boldieri ;
Nicoli, Fernanda Michely ;
Palazzo de Mello, Joao Carlos ;
Petereit, Frank ;
Luftmann, Heinrich .
QUIMICA NOVA, 2009, 32 (02) :412-416
[45]   Flavonoids as antioxidants [J].
Pietta, PG .
JOURNAL OF NATURAL PRODUCTS, 2000, 63 (07) :1035-1042
[46]   Antioxidant properties of phenolic compounds [J].
RiceEvans, CA ;
Miller, J ;
Paganga, G .
TRENDS IN PLANT SCIENCE, 1997, 2 (04) :152-159
[47]   New phenolic triterpenes from Maytenus blepharodes.: Semisynthesis of 6-deoxoblepharodol from pristimerin [J].
Rodríguez, FM ;
López, MR ;
Jiménez, IA ;
Moujir, L ;
Ravelo, AG ;
Bazzocchi, IL .
TETRAHEDRON, 2005, 61 (09) :2513-2519
[48]   Simultaneous determination of total hypericin and hyperforin in St. John's wort extracts by HPLC with electrochemical detection [J].
Rueckert, Ulla ;
Likussar, Werner ;
Michelitsch, Astrid .
PHYTOCHEMICAL ANALYSIS, 2007, 18 (03) :204-208
[49]   A flavonoid glycoside from Maytenus aquifolium [J].
Sannomiya, M ;
Vilegas, W ;
Rastrelli, L ;
Pizza, C .
PHYTOCHEMISTRY, 1998, 49 (01) :237-239
[50]   Preconcentration of rutin at a poly glutamic acid modified electrode and its determination by square wave voltammetry [J].
Santos, Daniela P. ;
Bergamini, Marcio F. ;
Santos, Vania A. F. F. M. ;
Furlan, Maysa ;
Zanoni, Maria Valnice B. .
ANALYTICAL LETTERS, 2007, 40 (16-18) :3430-3442