Diastereoselective cycloadditions of new trifluoromethyl azomethine ylides derived from trifluorothioacetamides

被引：19
作者：
Laduron, F [1 ]
Ates, C [1 ]
Viehe, HG [1 ]
机构：
[1] UNIV CATHOLIQUE LOUVAIN, ORGAN CHEM LAB, B-1348 LOUVAIN, BELGIUM
来源：
TETRAHEDRON LETTERS | 1996年 / 37卷 / 31期
关键词：
D O I：
10.1016/0040-4039(96)01185-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two methods of generation of new trifluoromethyl azomethine ylides are described: by heating N,N-dimethyl-bis(methylthio)-orthotrifluoroacetamide 2 or by deprotonation of trifluoromethyl thioamidium salts. Trapping by dipolarophiles leads to 2-trifluoromethyl pyrrolidines and pyrrolizidines with high diastereoselectivity. Copyright (C) 1996 Published by Elsevier Science Ltd
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页码：5515 / 5518
页数：4
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