Diastereoselective cycloadditions of new trifluoromethyl azomethine ylides derived from trifluorothioacetamides

被引：19

作者：

Laduron, F ^{[1
]}

Ates, C ^{[1
]}

Viehe, HG ^{[1
]}

机构：

[1] UNIV CATHOLIQUE LOUVAIN, ORGAN CHEM LAB, B-1348 LOUVAIN, BELGIUM

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 31期

关键词：

D O I：

10.1016/0040-4039(96)01185-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two methods of generation of new trifluoromethyl azomethine ylides are described: by heating N,N-dimethyl-bis(methylthio)-orthotrifluoroacetamide 2 or by deprotonation of trifluoromethyl thioamidium salts. Trapping by dipolarophiles leads to 2-trifluoromethyl pyrrolidines and pyrrolizidines with high diastereoselectivity. Copyright (C) 1996 Published by Elsevier Science Ltd

引用

页码：5515 / 5518

页数：4

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