Pseudomonas aeruginosa in the ICU: prevalence, resistance profile, and antimicrobial consumption

被引：19

作者：

da Silva Ribeiro, Aghata Cardoso ^{[1
]}

Lonardoni Crozatti, Marcia Terezinha ^{[1
]}

da Silva, Adilson Aderito ^{[2
]}

Macedo, Rodrigo Spineli ^{[3
]}

de Oliveira Machado, Antonia Maria ^{[4
]}

de Albuquerque Silva, Antonio Tavora ^{[1
]}

机构：

[1] Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Diadema, SP, Brazil

[2] Univ Presbiteriana Mackenzie, Ctr Ciencias Sociais & Aplicadas, Sao Paulo, SP, Brazil

[3] Univ Fed Sao Paulo, Hosp Univ UNIFESP, Hosp Sao Paulo, Sao Paulo, SP, Brazil

[4] Univ Fed Sao Paulo, Dept Med, Lab Cent, Hosp Sao Paulo, Sao Paulo, SP, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2020年 / 53卷

关键词：

Pseudomonas aeruginosa; Antimicrobial agents; Drug resistance; INTENSIVE-CARE-UNIT;

D O I：

10.1590/0037-8682-0498-2018

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: Pseudomonas aeruginosa is one of the main pathogens causing infection in intensive care units (ICUs) and usually presents antimicrobial resistance. Methods: Data were obtained from ICUs between 2010 and 2013. Results: P. aeruginosa had a prevalence of 14.5% of which 48.7% were multidrug resistant. We observed increasing resistance to carbapenems and polymyxin B and growing consumption of aminoglycosides, meropenem, ceftazidime, and polymyxin B. The regression impact between resistance and consumption was significant with respect to amikacin, imipenem. meropenem, and polymyxin B. Conclusions: Monitoring antimicrobial consumption and resistant microorganisms should be reinforced to combat antimicrobial- and multidrug resistance.

引用

页数：6

共 15 条

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