Inducible nitric oxide synthase inhibition by mycophenolic acid

被引:0
|
作者
Miljkovic, D
Markovic, M
Trajkovic, V
机构
[1] Inst Biol Res, Dept Neurobiol & Immunol, Belgrade, Serbia Monteneg, Serbia
[2] Sch Med, Inst Microbiol & Immunol, Belgrade, Serbia Monteneg, Serbia
关键词
mycophenolic acid; mycophenolate mofetil; nitric oxide; iNOS;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The focus of this review is the influence of an immunosuppressive xenobiotic drug mycophenolic acid on the induction of nitric oxide production in various cell types. The potential therapeutic significance of the cell-specific fine-tuning of nitric oxide release by mycophenolic acid, as well as the mechanisms behind the drug action are discussed.
引用
收藏
页码:741 / 746
页数:6
相关论文
共 50 条
  • [41] Inducible nitric oxide synthase inhibition attenuates renal Hemodynamics during pregnancy
    Alexander, BT
    Cockrell, K
    Cline, FD
    Granger, JP
    HYPERTENSION, 2002, 39 (02) : 586 - 590
  • [42] Inhibition of inducible nitric oxide synthase delays gastric ulcer healing in the rat
    Akiba, Y
    Nakamura, M
    Mori, M
    Suzuki, H
    Oda, M
    Kimura, H
    Miura, S
    Tsuchiya, M
    Ishii, H
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 1998, 27 : S64 - S73
  • [43] Inhibition of inducible Nitric Oxide Synthase by a mustard gas analog in murine macrophages
    Min Qui
    Victor M Paromov
    Hongsong Yang
    Milton Smith
    William L Stone
    BMC Cell Biology, 7
  • [44] Selective inhibition of inducible nitric oxide synthase prevents ischaemic brain injury
    Parmentier, S
    Böhme, GA
    Lerouet, D
    Damour, D
    Stutzmann, JM
    Margaill, I
    Plotkine, M
    BRITISH JOURNAL OF PHARMACOLOGY, 1999, 127 (02) : 546 - 552
  • [45] Effects of inducible nitric oxide synthase inhibition on cerebral edema in severe hypertension
    Takemori, K
    Ito, H
    Suzuki, T
    BRAIN EDEMA XI, 2000, 76 : 335 - 338
  • [46] Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes
    Bentz, Mireille
    Zaouter, Charlotte
    Shi, Qin
    Fahmi, Hassan
    Moldovan, Florina
    Fernandes, Julio C.
    Benderdour, Mohamed
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2012, 113 (07) : 2256 - 2267
  • [47] Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats
    Sukru Oter
    Ahmet Korkmaz
    Emin Oztas
    Ibrahim Yildirim
    Turgut Topal
    Hayati Bilgic
    Urological Research, 2004, 32 : 185 - 189
  • [48] What sense lies in antisense inhibition of inducible nitric oxide synthase expression?
    Hemmrich, K
    Kröncke, KD
    Suschek, CV
    Kolb-Bachofen, V
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2005, 12 (04): : 183 - 199
  • [49] Inducible Nitric Oxide Synthase Inhibition as a Target for the Treatment of Vascular Dysfunction in Hypertension
    Cau, Stefany B. A.
    Tostes, Rita C.
    HYPERTENSION, 2012, 59 (03) : E21 - E21
  • [50] Selective inhibition of inducible nitric oxide synthase exacerbates erosive joint disease
    McCartney-Francis, NL
    Song, XY
    Mizel, DE
    Wahl, SM
    JOURNAL OF IMMUNOLOGY, 2001, 166 (04): : 2734 - 2740