Inducible nitric oxide synthase inhibition by mycophenolic acid

被引：0
|
作者：
Miljkovic, D
Markovic, M
Trajkovic, V
机构：
[1] Inst Biol Res, Dept Neurobiol & Immunol, Belgrade, Serbia Monteneg, Serbia
[2] Sch Med, Inst Microbiol & Immunol, Belgrade, Serbia Monteneg, Serbia
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2004年 / 4卷 / 07期
关键词：
mycophenolic acid; mycophenolate mofetil; nitric oxide; iNOS;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The focus of this review is the influence of an immunosuppressive xenobiotic drug mycophenolic acid on the induction of nitric oxide production in various cell types. The potential therapeutic significance of the cell-specific fine-tuning of nitric oxide release by mycophenolic acid, as well as the mechanisms behind the drug action are discussed.
引用
收藏
页码：741 / 746
页数：6
相关论文
共 50 条
  • [1] Mycophenolic acid downregulates inducible nitric oxide synthase induction in astrocytes
    Miljkovic, D
    Samardzic, T
    Cvetkovic, I
    Stojkovic, MM
    Trajkovic, V
    GLIA, 2002, 39 (03) : 247 - 255
  • [2] Mycophenolic acid inhibits activation of inducible nitric oxide synthase in rodent fibroblasts
    Miljkovic, D
    Cvetkovic, I
    Stosic-Grujicic, S
    Trajkovic, V
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2003, 132 (02): : 239 - 246
  • [3] Inhibition of inducible nitric oxide synthase in respiratory diseases
    Hesslinger, Christian
    Strub, Andreas
    Boer, Rainer
    Ulrich, Wolf-Ruediger
    Lehner, Martin D.
    Braun, Clemens
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2009, 37 : 886 - 891
  • [4] Inducible nitric oxide synthase: Regulation, structure, and inhibition
    Cinelli, Maris A.
    Do, Ha T.
    Miley, Galen P.
    Silverman, Richard B.
    MEDICINAL RESEARCH REVIEWS, 2020, 40 (01) : 158 - 189
  • [5] Endothelial nitric oxide synthase deficiency and inducible nitric oxide synthase inhibition in the setting of septic cardiomyopathy
    A Van de Sandt
    R Windler
    A Gödecke
    J Ohlig
    S Becher
    E Van Faassen
    T Rassaf
    J Schrader
    M Kelm
    M Merx
    Critical Care, 13 (Suppl 1):
  • [6] Selective inducible nitric oxide synthase inhibition in septic shock
    Beilman, GJ
    CRITICAL CARE MEDICINE, 2001, 29 (11) : 2230 - 2231
  • [7] Selective Inhibition of Inducible Nitric Oxide Synthase by Derivatives of Acetamidine
    Maccallini, Cristina
    Patruno, Antonia
    Ammazzalorso, Alessandra
    De Filippis, Barbara
    Fantacuzzi, Marialuigia
    Franceschelli, Sara
    Giampietro, Letizia
    Masella, Simona
    Tricca, Maria Luisa
    Amoroso, Rosa
    MEDICINAL CHEMISTRY, 2012, 8 (06) : 991 - 995
  • [8] Inhibition of inducible nitric oxide synthase by sumaflavone isolated from Selaginella tamariscina
    Yang, JW
    Pokharel, YR
    Kim, MR
    Woo, ER
    Choi, HK
    Kang, KW
    JOURNAL OF ETHNOPHARMACOLOGY, 2006, 105 (1-2) : 107 - 113
  • [9] Characterisation of bovine inducible nitric oxide synthase
    Widdison, Stephanie
    Ashley, George R.
    Howard, Chris J.
    Coffey, Tracey J.
    VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2007, 117 (3-4) : 302 - 309
  • [10] Reduction of myocardial infarct size by inhibition of inducible nitric oxide synthase
    Wang, D
    Yang, XP
    Liu, YH
    Carretero, OA
    LaPointe, MC
    AMERICAN JOURNAL OF HYPERTENSION, 1999, 12 (02) : 174 - 182
12345