Nasopharyngeal Testing among Healthcare Workers (HCWs) of a Large University Hospital in Milan, Italy during Two Epidemic Waves of COVID-19

被引：11

作者：

Comelli, Agnese ^{[1
]}

Consonni, Dario ^{[2
]}

Lombardi, Andrea ^{[1
,3
]}

Viero, Giulia ^{[1
]}

Oggioni, Massimo ^{[4
]}

Bono, Patrizia ^{[4
]}

Renteria, Sara Colonia Uceda ^{[4
]}

Ceriotti, Ferruccio ^{[4
]}

Mangioni, Davide ^{[1
]}

Muscatello, Antonio ^{[1
]}

Piatti, Alessandra ^{[5
]}

Pesatori, Angela Cecilia ^{[2
,6
]}

Castaldi, Silvana ^{[7
,8
]}

Riboldi, Luciano ^{[9
]}

Bandera, Alessandra ^{[1
,3
,10
]}

Gori, Andrea ^{[1
,3
,10
]}

机构：

[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Infect Dis Unit, I-20122 Milan, Italy

[2] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Epidemiol Unit, I-20122 Milan, Italy

[3] Univ Milan, Dept Pathophysiol & Transplantat, I-20122 Milan, Italy

[4] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Clin Lab, I-20122 Milan, Italy

[5] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Med Direct, I-20122 Milan, Italy

[6] Univ Milan, Dept Clin Sci & Community Hlth, I-20122 Milan, Italy

[7] Univ Milan, Dept Biomed Sci Hlth, I-20122 Milan, Italy

[8] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Qual Unit, I-20122 Milan, Italy

[9] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Occupat Hlth Unit, I-20122 Milan, Italy

[10] Univ Milan, Ctr Multidisciplinary Res Hlth Sci MACH, I-20122 Milan, Italy

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2021年 / 18卷 / 16期

关键词：

COVID-19; SARS-CoV-2; healthcare operators; reinfection; nasopharyngeal swab; SARS-COV-2;

D O I：

10.3390/ijerph18168748

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Background: since October 2020, a second SARS-CoV-2 epidemic wave has hit Italy. We investigate the frequency of positive nasopharyngeal swabs among HCWs during the two waves and the association with occupation and demographic characteristics. Methods: this is a retrospective, observational study conducted in a large university hospital in Milan, Northern Italy. We defined two epidemic waves: 1st (February 2020-July 2020) and 2nd (August 2020-January 2021). Occupational and demographic characteristics of HCWs who underwent nasopharyngeal swabs for SARS-CoV-2 were collected. Results: in the 1st wave, 242 positive subjects (7.2%) were found among 3378 HCWs, whereas in the 2nd wave, the positive subjects were 545 out of 4465 (12.2%). In both epidemic waves positive NPSs were more frequent among HCWs with health-related tasks and lower among students (p < 0.001). However, in the 2nd wave, workers engaged in non-health-related tasks had a peak of 20.7% positivity. Among 160 positive HCWs in the 1st wave who were tested again in the 2nd wave, the rate of reinfection based on SARS-CoV2 RNA cycle quantification value was 0.6%. Conclusions: during the 2nd epidemic wave, we confirmed a significant impact of COVID-19 among HCWs. The rise of infection rate among HCWs seems to reflect the increasing spread of SARS-CoV-2 among the overall population.

引用

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