Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

被引：67
作者：
Razzaghi-Abyaneh, Mehdi
Yoshinari, Tomoya
Shams-Ghahfarokhi, Masoorneh
Rezaee, Mohammad-Bagher
Nagasawa, Hiromichi
Sakudat, Shohei
机构：
[1] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Tokyo 113, Japan
[2] Tarbiat Modares Univ, Fac Med Sci, Dept Mycol, Tehran 14115, Iran
[3] Inst Res Forest & Rangelands, Dept Med Plants, Tehran 13185, Iran
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2007年 / 71卷 / 09期
关键词：
aflatoxin; Aspergillus parasiticus; dillapiol; apiol; inhibitor;
D O I：
10.1271/bbb.70264
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Dillapiol was isolated from the essential oil of dill as a specitic inhibitor of aflatoxin G(1) production. It inhibited aflatoxin G(1) production by Aspergillus parasiticus with an IC50 value of 0.15 mu m without inhibiting aflatoxin B, production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 mu m, respectively.
引用
收藏
页码：2329 / 2332
页数：4
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