Receptors for collapsin/semaphorins

被引：119
作者：
Fujisawa, H [1 ]
Kitsukawa, T
机构：
[1] Nagoya Univ, Grad Sch Sci, Div Biol Sci, Grp Dev Neurobiol,Chikusa Ku, Nagoya, Aichi 4648602, Japan
[2] Natl Inst Basic Biol, Lab Specificat Mech, Okazaki, Aichi 4448585, Japan
来源：
CURRENT OPINION IN NEUROBIOLOGY | 1998年 / 8卷 / 05期
关键词：
D O I：
10.1016/S0959-4388(98)80085-8
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Chemorepulsive signals that repel or paralyze neuronal growth cones have been found to play important roles in axon guidance in a stereotyped manner. Recent progress in the identification of neuropilins as the receptors for class III secreted collapsin/semaphorin subfamily members, which are neuronal repellents, and in the analysis of mutant mice lacking neuropilin function has confirmed the importance of these chemorepellents in axon guidance. In addition, characterization of the neuropilin protein has yielded new insights into the functions of this molecule in vascular formation and in axon guidance.
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收藏
页码：587 / 592
页数：6
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