Applications of the combination of microwave and parallel synthesis in medicinal chemistry

被引：11

作者：

Alcazar, Jesus ^{[1
]}

Diels, Gaston ^{[2
]}

Schoentjes, Bruno ^{[3
]}

机构：

[1] Johnson & Johnson Pharmaceut Res & Dev, Div Janssen Cilag, Toledo, Spain

[2] Johnson & Johnson Res & Dev, Div Janssen Pharmaceut, B-2340 Beerse, Belgium

[3] Johnson & Johnson Pharmaceut Res & Dev, Div Janssen Cilag, F-27106 Val De Reuil, France

来源：

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING | 2007年 / 10卷 / 10期

关键词：

D O I：

10.2174/138620707783220383

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The blending of microwave heating and parallel chemistry is a logical consequence of the significant rate enhancement and higher product yield afforded by microwave technology and the increase in productivity afforded by combinatorial chemistry. For this reason, this combination has become increasingly popular in the organic chemistry community. The current review highlights the application of this approach as a way to increase the rate of analogue synthesis in medicinal chemistry.

引用

页码：918 / 932

页数：15

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