Transvaginal ultrasound-guided local methotrexate administration as the first-line treatment for cesarean scar pregnancy: Follow-up of 18 cases

被引：58

作者：

Cok, Tayfun ^{[1
]}

Kalayci, Hakan ^{[1
]}

Ozdemir, Halis ^{[1
]}

Haydardedeoglu, Bulent ^{[1
]}

Parlakgumus, Ayse H. ^{[1
]}

Tarim, Ebru ^{[1
]}

机构：

[1] Baskent Univ, Sch Med, Dept Obstet & Gynecol, TR-06490 Ankara, Turkey

来源：

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH | 2015年 / 41卷 / 05期

关键词：

cesarean scar pregnancy; ectopic pregnancy; local; methotrexate; ultrasound-guided; SECTION SCAR; ARTERIOVENOUS-MALFORMATION; ECTOPIC PREGNANCIES; MANAGEMENT OPTIONS; ASPIRATION; DIAGNOSIS;

D O I：

10.1111/jog.12627

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Cesarean scar pregnancy (CSP) is a rare type of ectopic pregnancy, which occurs in previous cesarean section scar tissue, with an incidence of 1 in 1800-3000 pregnancies. Transvaginal ultrasound-guided local methotrexate (MTX) administration presents as a non-systemic option with possible better penetration to the pregnancy site. We present the management of 18 patients with CSP solely by transvaginal ultrasound-guided local MTX administration. All patients were treated with local MTX with a dose of 50mg/m(2). Eleven (61.1%) of the patients did not need any further intervention. Four patients (22.2%) were treated with additional single-dose systemic MTX due to inadequate alteration in blood -human chorionic gonadotrophin levels. Three patients (16.7%) required hysteroscopy and/or laparotomy. We suggest that transvaginal ultrasound-guided local MTX treatment may be considered as a first-line treatment for CSP.

引用

页码：803 / 808

页数：6

共 16 条

[1] Cesarean Scar Pregnancy: A Rare Cause of Uterine Arteriovenous Malformation [J].