Recent Progress in Catalytic Synthesis of 1,2,3-Triazoles

被引:39
|
作者
De Nino, Antonio [1 ]
Maiuolo, Loredana [1 ]
Costanzo, Paola [1 ]
Algieri, Vincenzo [1 ]
Jiritano, Antonio [1 ]
Olivito, Fabrizio [1 ]
Tallarida, Matteo Antonio [1 ]
机构
[1] Univ Calabria, Dipartimento Chim & Tecnol Chim, Via P Bucci,Cubo 12-C, I-87036 Arcavacata Di Rende, CS, Italy
关键词
1; 2; 3-triazoles; click chemistry; 3-dipolar cycloaddition; Huisgen reactions; triazole synthesis; AZIDE-ALKYNE CYCLOADDITION; METAL-FREE ROUTE; REGIOSELECTIVE SYNTHESIS; ONE-POT; 1,5-DISUBSTITUTED 1,2,3-TRIAZOLES; 1,3-DIPOLAR CYCLOADDITION; IONIC LIQUID; 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES; MULTICOMPONENT REACTION; BIOLOGICAL EVALUATION;
D O I
10.3390/catal11091120
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
1,2,3-triazoles represent a functional heterocyclic core that has been at the center of modern organic chemistry since the beginning of click chemistry. Being a versatile framework, such an aromatic ring can be observed in uncountable molecules useful in medicine and photochemistry, just to name a few. This review summarizes the progress achieved in their synthesis from 2015 to today, with particular emphasis on the development of new catalytic and eco-compatible approaches. In doing so, we subdivided the report based on their degree of functionalization and, for each subparagraph, we outlined the role of the catalyst employed.
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页数:48
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