INCIDENCE OF INFLUENZA VIRUS INFECTION IN EARLY INFANCY A PROSPECTIVE STUDY IN SOUTH ASIA

被引：17

作者：

Henkle, Emily ^{[1
]}

Steinhoff, Mark C. ^{[1
,2
]}

Omer, Saad B. ^{[3
]}

Roy, Eliza ^{[4
]}

Arifeen, Shams E. ^{[4
]}

Raqib, Rubhana ^{[4
]}

McNeal, Monica ^{[2
]}

Breiman, Robert F. ^{[5
]}

Moss, William J. ^{[1
]}

Zaman, K. ^{[4
]}

机构：

[1] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD USA

[2] Cincinnati Childrens Hosp Med Ctr, Global Hlth Ctr, Cincinnati, OH 45229 USA

[3] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA

[4] Int Ctr Diarrhoeal Dis Res, Dhaka 1000, Bangladesh

[5] Ctr Dis Control & Prevent, Atlanta, GA USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2011年 / 30卷 / 02期

基金：

美国国家卫生研究院;

关键词：

influenza; infants; IMMUNIZATION; ANTIBODY; PREGNANCY; CHILDREN; MOTHERS;

D O I：

10.1097/INF.0b013e3181f63c39

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24-41). These data suggest a high burden of influenza in young infants in tropical South Asia.

引用

页码：170 / 173

页数：4

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