Elimination of chloride interference on arsenic speciation in ion chromatography inductively coupled mass spectrometry using an octopole collision/reaction system

Anion-exchange chromatography with inductively coupled plasma mass spectrometry (ICP-MS) is often used for the speciation of arsenic (As). In this work, either He or H-2 was introduced to the octopole collision/reaction cell to eliminate chloride (Cl-) interferences during As speciation by ICP-MS. Polyatomic species, (ArCl)-Ar-40-Cl-35 and (ArCl)-Ar-38-Cl-37, which are formed in high chloride matrices interfere with the ICP-MS detection of As-75. These interferences were reduced or eliminated by introducing He or H-2 to the collision/reaction cell, with some loss in sensitivity when compared to the standard mode (no gas). For example, the sensitivity of As(V) was 30.4 and 17.7% of that observed in standard mode when introducing He and H-2, respectively. Chloride interference was completely eliminated using a flow rate of 3.0 mL min(-1) with H-2 as a reaction gas with detection limits in the range of 0.3-0.6 mu g L-1. The developed method was applied to determination of arsenic species in waters containing high concentrations of chloride by following a simple procedure and without modification of the ICP-MS instrument. (C) 2007 Published by Elsevier B.V.