Wide-field high-speed space-division multiplexing optical coherence tomography using an integrated photonic device

被引:22
作者
Huang, Yongyang [1 ,2 ]
Badar, Mudabbir [1 ,2 ]
Nitkowski, Arthur [3 ]
Weinroth, Aaron [3 ]
Tansu, Nelson [1 ,2 ]
Zhou, Chao [1 ,2 ,4 ]
机构
[1] Lehigh Univ, Dept Elect & Comp Engn, 27 Mem Dr W, Bethlehem, PA 18015 USA
[2] Lehigh Univ, Ctr Photon & Nanoelect, 27 Mem Dr W, Bethlehem, PA 18015 USA
[3] Tornado Spectral Syst Inc, 555 Richmond St West,Suite 402, Toronto, ON M5V 3B1, Canada
[4] Lehigh Univ, Dept Bioengn, Bethlehem, PA 18015 USA
来源
BIOMEDICAL OPTICS EXPRESS | 2017年 / 8卷 / 08期
基金
美国国家科学基金会;
关键词
PROGRAMMABLE SWEPT-SOURCE; ANTERIOR SEGMENT; MEGAHERTZ OCT; DOMAIN OCT; 1310; NM; LASER; RESOLUTION; INTERFEROMETER; VISUALIZATION; MICROSCOPY;
D O I
10.1364/BOE.8.003856
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Space-division multiplexing optical coherence tomography (SDM-OCT) is a recently developed parallel OCT imaging method in order to achieve multi-fold speed improvement. However, the assembly of fiber optics components used in the first prototype system was labor-intensive and susceptible to errors. Here, we demonstrate a high-speed SDM-OCT system using an integrated photonic chip that can be reliably manufactured with high precisions and low per-unit cost. A three-layer cascade of 1 x 2 splitters was integrated in the photonic chip to split the incident light into 8 parallel imaging channels with similar to 3.7 mm optical delay in air between each channel. High-speed imaging (similar to 1s/volume) of porcine eyes ex vivo and wide-field imaging (similar to 18.0 x 14.3 mm(2)) of human fingers in vivo were demonstrated with the chip-based SDM-OCT system. (C) 2017 Optical Society of America
引用
收藏
页码:3856 / 3867
页数:12
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