Late Metabolic Acidosis Caused by Renal Tubular Acidosis in Acute Salicylate Poisoning

被引：5
作者：
Sakai, Norihiro [1 ]
Hirose, Yasuo [1 ]
Sato, Nobuhiro [1 ]
Kondo, Daisuke [2 ]
Shimada, Yuko [3 ]
Hori, Yasushi [3 ]
机构：
[1] Niigata City Gen Hosp, Dept Emergency & Crit Care Med, Niigata, Japan
[2] Niigata City Gen Hosp, Dept Nephrol, Niigata, Japan
[3] Niigata City Gen Hosp, Dept Hosp Pharm, Niigata, Japan
来源：
INTERNAL MEDICINE | 2016年 / 55卷 / 10期
关键词：
drug overdose; acid-base disturbance; renal tubular injury; ASPIRIN OVERDOSE; MANAGEMENT;
D O I：
10.2169/internalmedicine.55.5786
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 16-year-old man was transferred to our emergency department seven hours after ingesting 486 aspirin tablets. His blood salicylate level was 83.7 mg/dL. He was treated with fluid resuscitation and sodium bicarbonate infusion, and his condition gradually improved, with a decline in the blood salicylate level. However, eight days after admission, he again reported nausea, a venous blood gas revealed metabolic acidosis with a normal anion gap. The blood salicylate level was undetectable, and a urinalysis showed glycosuria, proteinuria and elevated beta-2 microglobulin and n-acetyl glucosamine levels, with a normal urinary pH despite the acidosis. We diagnosed him with relapse of metabolic acidosis caused by renal tubular acidosis.
引用
收藏
页码：1315 / 1317
页数：3
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