Onset of various CNS inflammatory demyelination diseases following COVID-19 vaccinations

被引:10
作者
Kim, Ki Hoon [1 ]
Kim, Su-Hyun [1 ]
Park, Na Young [1 ]
Hyun, Jae-Won [1 ]
Kim, Ho Jin [1 ]
机构
[1] Res Inst, Dept Neurol, 323 Ilsan Ro, Goyang 10408, South Korea
关键词
Multiple sclerosis; Neuromyelitis optica spectrum disorder; MOG antibody-associated disease; Demyelinating disease; COVID-19; vaccination;
D O I
10.1016/j.msard.2022.104141
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background: Since the start of COVID-19 vaccination worldwide, there have been several reports of inflammatory demyelinating diseases of the central nervous system (CNS-IDDs) following vaccination.Methods: We prospectively collected cases of new-onset CNS-IDDs with a temporal relationship between disease onset and COVID-19 vaccination and investigated their proportion among newly registered cases of CNS-IDD over the past year.Results: Among 117 cases, 10 (8.5%) had their first disease manifestation within one month following COVID-19 vaccination: 2 multiple sclerosis, 2 neuromyelitis optica spectrum disorder, 3 MOG antibody-associated disease, and 3 unclassified CNS-IDDs.Conclusion: This observation suggests that COVID-19 vaccination may trigger the onset of various CNS-IDDs in susceptible individuals.
引用
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页数:7
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