Antimicrobial effect of different types of honey on Staphylococcus aureus

被引:84
作者
Almasaudi, Saad B. [1 ]
Al-Nahari, Alaa A. M. [1 ]
Abd El-Ghany, El Sayed M. [2 ]
Barbour, Elie [3 ,4 ]
Al Muhayawi, Saad M. [5 ]
Al-Jaouni, Soad [6 ]
Azhar, Esam [7 ]
Qari, Mohamad [6 ]
Qari, Yousef A. [8 ]
Harakeh, Steve [7 ]
机构
[1] King Abdulaziz Univ, Fac Sci, Dept Biol, Jeddah, Saudi Arabia
[2] Zagazig Univ, Fac Med, Dept Microbiol & Immunol, Zagazig, Egypt
[3] Amer Univ Beirut, Dept Anim & Vet Sci, Fac Agr & Food Sci, Beirut, Lebanon
[4] King Abdulaziz Univ, Dept Biochem, Jeddah, Saudi Arabia
[5] King Abdulaziz Univ, Fac Med, Jeddah, Saudi Arabia
[6] King Abdulaziz Univ, Fac Med, Dept Hematol, Prophet Med, Jeddah, Saudi Arabia
[7] King Abdulaziz Univ, King Fahd Med Res Ctr, Special Infect Agents Unit, Jeddah, Saudi Arabia
[8] King Abdulaziz Univ Hosp, Dept Med, Jeddah, Saudi Arabia
关键词
Manuka Honey; Sidr honey; Nigella sativa honey; Methicillin resistant Staphylococcus aureus (MRSA); Saudi Arabia; ANTIBACTERIAL ACTIVITY; CLINICAL-SIGNIFICANCE; BIOFILM; BACTERIA; STRAINS;
D O I
10.1016/j.sjbs.2016.08.007
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Honey exhibits antimicrobial activities against a wide range of bacteria in different milieu. This study aims to compare the effects of five types of honey (both imported and local Saudi honey) against Staphylococcus aureus. The five types of honey (Manuka Honey UMF + 20, Manuka Honey UMF + 16, Active + 10 Manuka Honey, Sidr honey and Nigella sativa honey) were evaluated for their bactericidal/bacteriostatic activities against both methicillin resistant and sensitive S. aureus. The inhibitory effect of honey on bacterial growth was evident at concentrations of 20% and 10% (v/v). Manuka Honey showed the best results. Manuka Honey UMF + 20 had a bactericidal effect on both methicillin resistant and sensitive S. aureus. However, Sidr and N. sativa honey exerted only a bacteriostatic effect. The efficacy of different types of honey against S. aureus was dependent on the type of honey and the concentration at which it was administered. Manuka Honey had the best bactericidal activity. Future experiments should be conducted to evaluate the effects of honey on bacterial resistance. (C) 2016 Production and hosting by Elsevier B.V. on behalf of King Saud University.
引用
收藏
页码:1255 / 1261
页数:7
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