Dorsal skinfold titanium chamber for non-invasive imaging in nude mice using multiphoton and harmonic generation microscopy

被引：2

作者：

Li, FC ^{[1
]}

Wang, CC ^{[1
]}

Lin, SJ ^{[1
]}

Jee, SH ^{[1
]}

Dong, CY ^{[1
]}

机构：

[1] Natl Taiwan Univ, Dept Phys, Microscop Biophys Lab, Taipei 106, Taiwan

来源：

APBP 2004: SECOND ASIAN AND PACIFIC RIM SYMPOSIUM ON BIOPHOTONICS, PROCEEDINGS | 2004年

关键词：

D O I：

10.1109/APBP.2004.1412343

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

For many years, the dorsal skinfold chamber has been used for intravital observation in animal models. We have developed a chamber built using medical-grade titanium. Our design allows long-term, high resolution, and large-area observation in nude mice in vivo. Combined with two-photon fluorescence and second-harmonic generation microscopy, our chamber can be used to obtain qualitative and quantitative information for in vivo analysis of diseases such as tumors.

引用

页码：185 / 186

页数：2

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