Anti-colorectal cancer effects of seaweed-derived bioactive compounds

被引:10
作者
Fu, Yunhua [1 ]
Xie, Dong [1 ]
Zhu, Yinghao [1 ]
Zhang, Xinyue [2 ]
Yue, Hao [1 ]
Zhu, Kai [1 ]
Pi, Zifeng [1 ]
Dai, Yulin [1 ]
机构
[1] Changchun Univ Chinese Med, Changchun, Peoples R China
[2] Jilin Acad Agr Machinery, Changchun, Peoples R China
关键词
colorectal cancer; therapeutic compounds; Chlorophyta; Rhodophyta; Phaeophyta; POLYUNSATURATED FATTY-ACIDS; PHLOROGLUCINOL INDUCES APOPTOSIS; COLON-CANCER; KAPPA-CARRAGEENAN; ANTICANCER ACTIVITY; CYTOTOXIC ACTIVITY; LINOLEIC-ACID; MARINE POLYSACCHARIDES; KAPPAPHYCUS-ALVAREZII; SULFATED MODIFICATION;
D O I
10.3389/fmed.2022.988507
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Seaweeds are classified as Chlorophyta, Rhodophyta, and Phaeophyta. They constitute a number of the most significant repositories of new therapeutic compounds for human use. Seaweed has been proven to possess diverse bioactive properties, which include anticancer properties. The present review focuses on colorectal cancer, which is a primary cause of cancer-related mortality in humans. In addition, it discusses various compounds derived from a series of seaweeds that have been shown to eradicate or slow the progression of cancer. Therapeutic compounds extracted from seaweed have shown activity against colorectal cancer. Furthermore, the mechanisms through which these compounds can induce apoptosis in vitro and in vivo were reviewed. This review emphasizes the potential utility of seaweeds as anticancer agents through the consideration of the capability of compounds present in seaweeds to fight against colorectal cancer.
引用
收藏
页数:14
相关论文
共 174 条
  • [1] Health benefit of fucosterol from marine algae: a review
    Abdul, Qudeer Ahmed
    Choi, Ran Joo
    Jung, Hyun Ah
    Choi, Jae Sue
    [J]. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2016, 96 (06) : 1856 - 1866
  • [2] Systemic Evaluation of Mechanism of Cytotoxicity in Human Colon Cancer HCT-116 Cells of Silver Nanoparticles Synthesized Using Marine Algae Ulva lactuca Extract
    Acharya, Diptikanta
    Satapathy, Sagarika
    Yadav, Kanti Kusum
    Somu, Prathap
    Mishra, Gitanjali
    [J]. JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2022, 32 (02) : 596 - 605
  • [3] Ahmed O., 2014, Journal of Cancer Science and Therapy, V6, P202, DOI [10.4172/1948-5956.1000272, DOI 10.4172/1948-5956.1000272]
  • [4] Ali MS, 2019, REP BIOCHEM MOL BIOL, V8, P216
  • [5] Algae from Portuguese Coast Presented High Cytotoxicity and Antiproliferative Effects on an In vitro Model of Human Colorectal Cancer
    Alves, Celso
    Pinteus, Susete
    Rodrigues, Ana
    Horta, Andre
    Pedrosa, Rui
    [J]. PHARMACOGNOSY RESEARCH, 2018, 10 (01): : 24 - 30
  • [6] Marine Microalgae with Anti-Cancer Properties
    Andrade, Kevin A. Martinez
    Lauritano, Chiara
    Romano, Giovanna
    Ianora, Adrianna
    [J]. MARINE DRUGS, 2018, 16 (05):
  • [7] DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii
    Andrianasolo, EH
    France, D
    Cornell-Kennon, S
    Gerwick, WH
    [J]. JOURNAL OF NATURAL PRODUCTS, 2006, 69 (04): : 576 - 579
  • [8] Advance research in biomedical applications on marine sulfated polysaccharide
    Arokiarajan, Mary Shamya
    Thirunavukkarasu, Rajasekar
    Joseph, Jerrine
    Ekaterina, Obluchinskaya
    Aruni, Wilson
    [J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 194 : 870 - 881
  • [9] Effect of dietary β-sitosterol on fecal bacterial and colonic biotransformation enzymes in 1,2-dimethylhydrazine-induced colon carcinogenesis
    Arul, Albert Baskar
    Al Numair, Khalid
    Al Saif, Mohammed
    Savarimuthu, Ignacimuthu
    [J]. TURKISH JOURNAL OF MEDICAL SCIENCES, 2012, 42 : 1307 - 1313
  • [10] Arachidonic acid induces ER stress and apoptosis in HT-29 human colon cancer cells
    Bae, Sijeong
    Kim, Min-Kyoung
    Kim, Hong Seok
    Moon, Young-Ah
    [J]. ANIMAL CELLS AND SYSTEMS, 2020, 24 (05) : 260 - 266