Anti-colorectal cancer effects of seaweed-derived bioactive compounds

被引：11

作者：

Fu, Yunhua ^{[1
]}

Xie, Dong ^{[1
]}

Zhu, Yinghao ^{[1
]}

Zhang, Xinyue ^{[2
]}

Yue, Hao ^{[1
]}

Zhu, Kai ^{[1
]}

Pi, Zifeng ^{[1
]}

Dai, Yulin ^{[1
]}

机构：

[1] Changchun Univ Chinese Med, Changchun, Peoples R China

[2] Jilin Acad Agr Machinery, Changchun, Peoples R China

来源：

FRONTIERS IN MEDICINE | 2022年 / 9卷

关键词：

colorectal cancer; therapeutic compounds; Chlorophyta; Rhodophyta; Phaeophyta; POLYUNSATURATED FATTY-ACIDS; PHLOROGLUCINOL INDUCES APOPTOSIS; COLON-CANCER; KAPPA-CARRAGEENAN; ANTICANCER ACTIVITY; CYTOTOXIC ACTIVITY; LINOLEIC-ACID; MARINE POLYSACCHARIDES; KAPPAPHYCUS-ALVAREZII; SULFATED MODIFICATION;

D O I：

10.3389/fmed.2022.988507

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Seaweeds are classified as Chlorophyta, Rhodophyta, and Phaeophyta. They constitute a number of the most significant repositories of new therapeutic compounds for human use. Seaweed has been proven to possess diverse bioactive properties, which include anticancer properties. The present review focuses on colorectal cancer, which is a primary cause of cancer-related mortality in humans. In addition, it discusses various compounds derived from a series of seaweeds that have been shown to eradicate or slow the progression of cancer. Therapeutic compounds extracted from seaweed have shown activity against colorectal cancer. Furthermore, the mechanisms through which these compounds can induce apoptosis in vitro and in vivo were reviewed. This review emphasizes the potential utility of seaweeds as anticancer agents through the consideration of the capability of compounds present in seaweeds to fight against colorectal cancer.

引用

页数：14

共 174 条

[1] Health benefit of fucosterol from marine algae: a review [J].

Abdul, Qudeer Ahmed ;

Choi, Ran Joo ;

Jung, Hyun Ah ;

Choi, Jae Sue .

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2016, 96 (06) :1856-1866

[2] Systemic Evaluation of Mechanism of Cytotoxicity in Human Colon Cancer HCT-116 Cells of Silver Nanoparticles Synthesized Using Marine Algae Ulva lactuca Extract [J].

Acharya, Diptikanta ;

Satapathy, Sagarika ;

Yadav, Kanti Kusum ;

Somu, Prathap ;

Mishra, Gitanjali .

JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2022, 32 (02) :596-605

[3]

Ahmed O., 2014, Journal of Cancer Science and Therapy, V6, P202, DOI DOI 10.4172/1948-5956.1000272

[4]

Ali MS, 2019, REP BIOCHEM MOL BIOL, V8, P216

[5] Algae from Portuguese Coast Presented High Cytotoxicity and Antiproliferative Effects on an In vitro Model of Human Colorectal Cancer [J].

Alves, Celso ;

Pinteus, Susete ;

Rodrigues, Ana ;

Horta, Andre ;

Pedrosa, Rui .

PHARMACOGNOSY RESEARCH, 2018, 10 (01) :24-30

[6] Marine Microalgae with Anti-Cancer Properties [J].

Andrade, Kevin A. Martinez ;

Lauritano, Chiara ;

Romano, Giovanna ;

Ianora, Adrianna .

MARINE DRUGS, 2018, 16 (05)

[7] DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii [J].

Andrianasolo, EH ;

France, D ;

Cornell-Kennon, S ;

Gerwick, WH .

JOURNAL OF NATURAL PRODUCTS, 2006, 69 (04) :576-579

[8] Advance research in biomedical applications on marine sulfated polysaccharide [J].

Arokiarajan, Mary Shamya ;

Thirunavukkarasu, Rajasekar ;

Joseph, Jerrine ;

Ekaterina, Obluchinskaya ;

Aruni, Wilson .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 194 :870-881

[9] Effect of dietary β-sitosterol on fecal bacterial and colonic biotransformation enzymes in 1,2-dimethylhydrazine-induced colon carcinogenesis [J].

Arul, Albert Baskar ;

Al Numair, Khalid ;

Al Saif, Mohammed ;

Savarimuthu, Ignacimuthu .

TURKISH JOURNAL OF MEDICAL SCIENCES, 2012, 42 :1307-1313

[10] Arachidonic acid induces ER stress and apoptosis in HT-29 human colon cancer cells [J].

Bae, Sijeong ;

Kim, Min-Kyoung ;

Kim, Hong Seok ;

Moon, Young-Ah .

ANIMAL CELLS AND SYSTEMS, 2020, 24 (05) :260-266

← 1 2 3 4 5 6 7 8 9 10 →