Paraneoplastic limbic encephalitis - case report and review of literature

被引:16
作者
Munshi, SK
Thanvi, B
Chin, SK
Hubbard, I
Fletcher, A
Vallance, TR
机构
[1] Univ Hosp Leicester, Leicester Gen Hosp, Dept Cerebrovasc Med & Med Elderly, Leicester LE5 4PW, Leics, England
[2] Leicester Royal Infirm, Dept Med Elderly, Leicester LE1 5WW, Leics, England
[3] Gen Hosp Kettering, Dept Med, Kettering, Northants, England
[4] Leicester Royal Infirm, Dept Pathol, Leicester LE1 5WW, Leics, England
关键词
dementia; paraneoplastic syndrome; limbic encephalitis; elderly;
D O I
10.1093/ageing/afi017
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
We report a 77-year old man who presented with a sub-acute dementia associated with aggressive behaviour, ataxia, rapid progression and death. No cause for his illness could be detected in his lifetime, but at post mortem he was found to have paraneoplastic limbic encephalitis and a bronchogenic tumour. A diagnosis of paraneoplastic limbic encephalitis should be considered in the differential diagnosis of unexplained dementias and appropriate investigations performed to diagnose the condition.
引用
收藏
页码:190 / 193
页数:4
相关论文
共 12 条
[1]   Limbic encephalitis and small cell lung cancer - Clinical and immunological features [J].
Alamowitch, S ;
Graus, F ;
Uchuya, M ;
Rene, R ;
Bescansa, E ;
Delattre, JY .
BRAIN, 1997, 120 :923-928
[2]  
ALLOZI MT, 2001, HARRISONS PRINCIPLES, V101, P636
[3]   Paraneoplastic limbic encephalitis in Hodgkin's disease [J].
Deodhare, S ;
OConnor, P ;
Ghazarian, D ;
Bilbao, JM .
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 1996, 23 (02) :138-140
[4]   Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients [J].
Gultekin, SH ;
Rosenfeld, MR ;
Voltz, R ;
Eichen, J ;
Posner, JB ;
Dalmau, J .
BRAIN, 2000, 123 :1481-1494
[5]   ANTINERVOUS SYSTEM AUTOANTIBODIES IN PARANEOPLASTIC NEUROLOGICAL SYNDROMES [J].
HONNORAT, J ;
ANTOINE, JC .
REVUE DE MEDECINE INTERNE, 1994, 15 (02) :124-133
[6]  
Kaiser R, 1999, NERVENARZT, V70, P688, DOI 10.1007/s001150050498
[7]  
Lieberman FS, 2002, ONCOLOGY-NY, V16, P1539
[8]  
LIEBERMAN FS, 2002, ONCOLOGY HUNTINGTON, V16, P1550
[9]  
LIEBERMAN FS, 2002, ONCOLOGY HUNTINGTON, V16, P1554
[10]   Paraneoplastic limbic encephalitis in two teenage girls [J].
Rosenbaum, T ;
Gartner, J ;
Korholz, D ;
Janssen, G ;
Schneider, D ;
Engelbrecht, V ;
Gobel, U ;
Lenard, HG .
NEUROPEDIATRICS, 1998, 29 (03) :159-162