Anterolateral Thigh Fascia Lata Rescue Flap: A New Weapon in the Battle Against Osteoradionecrosis

被引:16
作者
Meleca, Joseph B. [1 ]
Kerr, Rhorie P. [2 ]
Prendes, B. L. [1 ]
Fritz, Michael A. [1 ]
机构
[1] Cleveland Clin, Facial Plast & Microvasc Surg, Cleveland, OH 44106 USA
[2] Univ Calif Los Angeles, Head & Neck Surg, Los Angeles, CA USA
关键词
Osteoradionecrosis; ORN fascia lata free flap; fascia lata; rescue flap; free flap; free-tissue transfer; vascularized fascia lata; anterolateral thigh flap; fascial flap; HYPERBARIC-OXYGEN THERAPY; FREE-TISSUE TRANSFER; HEAD;
D O I
10.1002/lary.29709
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Objectives To demonstrate that the anterolateral thigh fascia lata (ALTFL) rescue flap may be effectively used for management of osteoradionecrosis (ORN) in selected patients. Study Design Retrospective case review. Methods Retrospective chart review was performed on patients who underwent ALTFL free flap repair to various sites of ORN in the head and neck between 2011 and 2018. Inclusion criteria were patients with radiographic and clinical evidence of head and neck ORN who either failed previous hyperbaric oxygen (HBO) therapy or with extensive disease, which was unlikely to respond to conservative management. Results Twenty-three patients with average age of 63 years (40-78) who underwent 24 ALTFL free flap procedures were reviewed. ORN sites were the mandible (n = 16), palatomaxilla (n = 4), skull base and cervical spine (n = 3), and calvarium (n = 2). Recipient vessels used were superficial temporal (n = 11), common facial (n = 10), and angular (n = 3). Average hospital stay was 3.0 (1-10) days. Prior HBO therapy was performed in 13 (57%) patients. There were four major complications: flap failure, recurrent mandibular infection resolved with IV antibiotic course, mandibular fracture with malunion requiring occlusal adjustment, and unresolved sequelae of ORN requiring fibular free flap. There were four minor complications: thigh hematoma, thigh seroma, and intraoral scar formation causing trismus (n = 2). The procedure was successful in 22 of 23 (95.7%) patients with radiographic arrest of ORN, resolution of symptoms, and elimination of antibiotic requirements. Conclusion The ALTFL rescue flap merits strong consideration in ORN management and appears to prevent progression to more extensive disease, which would require full segmental bone resection and reconstruction. Level of Evidence 4 Laryngoscope, 2021
引用
收藏
页码:2688 / 2693
页数:6
相关论文
共 12 条
  • [1] Early cellular alterations in bone after radiation therapy and its relation to osteoradionecrosis
    Al-Nawas, B
    Duschner, H
    Grötz, KA
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2004, 62 (08) : 1045 - 1045
  • [2] Hyperbaric oxygen therapy for radionecrosis of the jaw:: A randomized, placebo-controlled, double-blind trial from the ORN96 Study Group
    Annane, D
    Depondt, J
    Aubert, P
    Villart, M
    Géhanno, P
    Gajdos, P
    Chevret, S
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (24) : 4893 - 4900
  • [3] New foundations in understanding osteonecrosis of the jaws
    Assael, LA
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2004, 62 (02) : 125 - 126
  • [4] Dambrain R., 1993, Revue de Stomatologie et de Chirurgie Maxillo-Faciale, V94, P140
  • [5] The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway
    Delanian, S
    Lefaix, JL
    [J]. RADIOTHERAPY AND ONCOLOGY, 2004, 73 (02) : 119 - 131
  • [6] Short-stay hospital admission after free tissue transfer for head and neck reconstruction
    Devine, Conor M.
    Haffey, Timothy M.
    Trosman, Samuel
    Fritz, Michael A.
    [J]. LARYNGOSCOPE, 2016, 126 (12) : 2679 - 2683
  • [7] Mandibular rescue: Application of the ALT fascia free flap to arrest osteoradionecrosis of the mandible
    Haffey, Timothy
    Winters, Ryan
    Kerr, Rhorie
    Fritz, Michael
    [J]. AMERICAN JOURNAL OF OTOLARYNGOLOGY, 2019, 40 (06)
  • [8] Use of Angular Vessels in Head and Neck Free-Tissue Transfer A Comprehensive Preclinical Evaluation
    Haffey, Timothy M.
    McBride, Jennifer M.
    Fritz, Michael A.
    [J]. JAMA FACIAL PLASTIC SURGERY, 2014, 16 (05) : 348 - 351
  • [9] A NEW CONCEPT IN THE TREATMENT OF OSTEORADIONECROSIS
    MARX, RE
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1983, 41 (06) : 351 - 357
  • [10] Hyperbaric oxygen therapy in the treatment of radio-induced lesions in normal tissues: a literature review
    Pasquier, D
    Hoelscher, T
    Schmutz, J
    Dische, S
    Mathieu, D
    Baumann, M
    Lartigau, E
    [J]. RADIOTHERAPY AND ONCOLOGY, 2004, 72 (01) : 1 - 13