Versatile Synthesis of 2-(Substituted phenyl)-6,7-dihydro-1H-indol-4(5H)-ones from Morita-Baylis-Hillman Acetates of 2-Oxo-2-(substituted phenyl)acetaldehyde

被引：24

作者：

Batchu, Harikrishna ^{[1
]}

Batra, Sanjay ^{[1
]}

机构：

[1] CSIR Cent Drug Res Inst, Med & Proc Chem Div, Lucknow 226001, Uttar Pradesh, India

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 2012卷 / 15期

关键词：

Nitrogen heterocycles; Synthetic methods; Indole Derivatives; Morita-Baylis-Hillman; FACILE SYNTHESIS; 4-SUBSTITUTED INDOLES; EFFICIENT SYNTHESIS; STEP SYNTHESIS; DERIVATIVES; 4-OXO-4,5,6,7-TETRAHYDROINDOLES; OXIDATION; (S)-(-)-PINDOLOL; ARYLGLYOXALS; HETEROCYCLES;

D O I：

10.1002/ejoc.201200107

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A versatile synthesis of 2-(substituted phenyl)-6,7-dihydro-1H-indol-4(5H)-ones from adducts of the MoritaBaylisHillman reaction between 2-oxo-2-(substituted phenyl)acetaldehydes and cyclohex-2-enone under mild conditions is described.

引用

页码：2935 / 2944

页数：10

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