Predictive Factors of Idiopathic Thrombocytopenic Purpura and Long-term Survival in Chinese Adults Undergoing Laparoscopic Splenectomy

被引：12

作者：

Xu, Tao ^{[1
]}

Li, Ning ^{[1
]}

Jin, Fa ^{[1
]}

Wu, Keren ^{[1
]}

Ye, Zhipeng ^{[1
]}

机构：

[1] Zhejiang Chinese Med Univ, Affiliated Hosp 1, Dept Hepatobiliary Surg, Hangzhou 310005, Zhejiang, Peoples R China

来源：

SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES | 2016年 / 26卷 / 05期

关键词：

idiopathic thrombocytopenic purpura; laparoscopic splenectomy; peak platelet count; age; predictive factor; long-term outcomes; PROGNOSTIC-FACTORS; FOLLOW-UP; INFECTION; CRITERIA;

D O I：

10.1097/SLE.0000000000000314

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The study aimed to investigate the long-term outcomes of laparoscopic splenectomy (LS) in Chinese patients with chronic idiopathic thrombocytopenic purpura (ITP). This was a retrospective analysis of 114 patients with ITP who underwent LS from 2001 to 2013. Patients were classified according to response at last contact: complete response (CR), partial response (PR), and no response (NR). Patients with CR had the highest platelet levels and patients with NR had the lowest. A correlation was observed between postoperative peak platelet count and platelet count on 2-month postoperative (r=0.829, P<0.01). In total, 27 patients showed NR to LS. Ten patients recurred within 3 years. The 140-month response rate to LS was 68%. Multivariate analysis showed that age and postoperative platelet count were independently associated with CR/PR. In conclusion, LS achieved good outcomes in Chinese patients with ITP. Age and postoperative peak platelet were independently associated with response.

引用

页码：397 / 400

页数：4

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