β-ketoimine as an efficient ligand for copper-catalyzed N-arylation of nitrogen-containing heterocycles with aryl halides

被引：29
|
作者：
Xue, Fei [1 ]
Cai, Chengyi [1 ]
Sun, Hongmei [1 ]
Shen, Qi [1 ]
Rui, Jiao [1 ]
机构：
[1] Suzhou Soochow Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
来源：
TETRAHEDRON LETTERS | 2008年 / 49卷 / 28期
基金：
中国国家自然科学基金;
关键词：
beta-ketoimine copper-catalyzed; coupling; N-arylation; imidazole; arylbromide;
D O I：
10.1016/j.tetlet.2008.05.008
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient copper catalyst system, Cu2O/beta-ketoimine L-1, for the N-arylation of nitrogen-containing heterocycles with aryl iodides and bromides has been developed. The system works well with the electron-rich, -neutral, and -deficient aryl bromides to afford the products in good to excellent yields. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4386 / 4389
页数：4
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