A case of angiosarcoma of the breast

被引：29

作者：

Ohta, M ^{[1
]}

Tokuda, Y ^{[1
]}

Kuge, S ^{[1
]}

Okumura, A ^{[1
]}

Tanaka, M ^{[1
]}

Kubota, M ^{[1
]}

Tajima, T ^{[1
]}

Akatsuka, A ^{[1
]}

Osamura, RY ^{[1
]}

Tamaoki, N ^{[1
]}

Mitomi, T ^{[1
]}

机构：

[1] TOKAI UNIV, SCH MED, DEPT SURG, ISEHARA, KANAGAWA 25911, JAPAN

来源：

JAPANESE JOURNAL OF CLINICAL ONCOLOGY | 1997年 / 27卷 / 02期

关键词：

angiosarcoma; breast; endoglin;

D O I：

10.1093/jjco/27.2.91

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This is a case report of a 20-year-old woman who had primary angiosarcoma of the left breast, with metastases to the spleen and ovary, Eight months after detecting a mass in her breast, she underwent mastectomy with biopsy of the ipsilateral axillary lymph nodes, splenectomy and bilateral oophorectomy, Five months after the operation, the patient succumbed to lung metastases. Angiosarcoma of the breast is a rare condition with a poor prognosis, and there are no established chemotherapeutic regimens as yet. Immunohistochemical staining for endoglin, known to be expressed mainly on the surface of endothelial cells, was positive. This suggests the possibility of treating angiosarcoma with anti-endoglin monoclonal antibodies.

引用

页码：91 / 94

页数：4

共 37 条

[1]

AGARWAL P K, 1977, Indian Journal of Cancer, V14, P182

[2] VASCULAR TUMORS OF THE MAMMARY-GLAND - A HISTOCHEMICAL AND ULTRASTRUCTURAL-STUDY [J].

ALVAREZFERNANDEZ, E ;

SALINEROPANIAGUA, E .

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1981, 394 (1-2) :31-47

[3]

ANTMAN KH, 1982, CANCER, V50, P2000, DOI 10.1002/1097-0142(19821115)50:10<2000::AID-CNCR2820501004>3.0.CO

[4]

2-U

[5] HAEMANGIOBLASTOMA OF THE BREAST ASSOCIATED WITH PREGNANCY [J].

BATCHELOR, GB .

BRITISH JOURNAL OF SURGERY, 1959, 46 (200) :647-649

[6]

Borrmann R, 1907, BEITR PATHOL ANAT AL, V40, P372

[7] ERADICATION OF LARGE SOLID TUMORS IN MICE WITH AN IMMUNOTOXIN DIRECTED AGAINST TUMOR VASCULATURE [J].

BURROWS, FJ ;

THORPE, PE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (19) :8996-9000

[8]

BURROWS FJ, 1992, CANCER RES, V52, P5954

[9]

BYERS VS, 1988, IMMUNOLOGY, V65, P329

[10]

CHEN KTK, 1980, CANCER-AM CANCER SOC, V46, P368, DOI 10.1002/1097-0142(19800715)46:2<368::AID-CNCR2820460226>3.0.CO

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